Results 61 to 70 of about 8,657,643 (253)

Challenges for inclusive education [PDF]

open access: yes, 2001
vii, 76 leaves ; 29 cm. --This study attempted to discover teachers' perceptions of the success of inclusive education - inclusion of learning disabled students - in the junior high schools of Westwind School Division #74.
University of Lethbridge. Faculty of Education   +1 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Bridging awareness and behavior: decoding implicit metacognitive behaviors in AI-assisted programming via fine-grained log analysis

open access: yesFrontiers in Psychology
While generative artificial intelligence offers transformative potential for programming education, its impact on students' internal cognitive and behavioral patterns remains underexplored.
Xiaojing Hou   +3 more
doaj   +1 more source

Introducing Programming and Digital Competence in Swedish K–9 Education [PDF]

open access: yes, 2017
The role of computer science and IT in Swedish schools has varied throughout the years. In fall 2014, the Swedish government gave the National Agency for Education (Skolverket) the task of preparing a proposal for K–9 education on how to better address ...
Heintz, Fredrik   +15 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

An Educational Ontology for Introductory Python Programming: Structuring Knowledge to Enable Personalization

open access: yesIEEE Access
Personalized learning has gained significant attention in recent years in response to the limitations of one-size-fits-all approaches to teaching, particularly in areas such as programming education where learners vary widely in prior knowledge, pace and
Ines Obradovic   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Craft Ethics : Aiming for Virtue in Programming with Generative AI

open access: yes
This paper analyses some aspects of the profound shifts in programming practice and education about bythe advent of generative AI (GenAI). As GenAI tools become increasingly integrated into programmingenvironments, they offer an approach to programming ...
Tholander, Jakob, Jonsson, Martin
core   +4 more sources

Four approaches to teaching programming

open access: yes, 2011
Based on a survey of literature, four different approaches to teaching introductory programming are identified and described. Examples of the practice of each approach are identified representing procedural, visual, and object-oriented programming ...
Selby, Cynthia
core   +1 more source

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