Results 31 to 40 of about 5,027,565 (330)

Metabolic Reprogramming and Epithelial-Mesenchymal Plasticity: Opportunities and Challenges for Cancer Therapy

Frontiers in Oncology, 2020
Metabolic reprogramming and epithelial-mesenchymal plasticity are both hallmarks of the adaptation of cancer cells for tumor growth and progression. For metabolic changes, cancer cells alter metabolism by utilizing glucose, lipids, and amino acids to ...
Nai-Yun Sun, Nai-Yun Sun, Muh-Hwa Yang, Muh-Hwa Yang, Muh-Hwa Yang   +4 more
doaj   +1 more source

Every which way? On predicting tumor evolution using cancer progression models [PDF]

, 2019
Successful prediction of the likely paths of tumor progression is valuable for diagnostic, prognostic, and treatment purposes. Cancer progression models (CPMs) use cross-sectional samples to identify restrictions in the order of accumulation of driver ...
Díaz-Uriarte, Ramón, Vasallo, Claudia
core   +2 more sources

Targeting the Formyl Peptide Receptor type 1 to prevent the adhesion of ovarian cancer cells onto mesothelium and subsequent invasion

Journal of Experimental & Clinical Cancer Research, 2019
Background The biological behavior of epithelial ovarian cancer (EOC) is unique since EOC cells metastasize early to the peritoneum. Thereby, new anti-target agents designed to block trans-coelomic dissemination of EOC cells may be useful as anti ...
Michele Minopoli, Giovanni Botti, Vincenzo Gigantino, Concetta Ragone, Sabrina Sarno, Maria Letizia Motti, Giosuè Scognamiglio, Stefano Greggi, Cono Scaffa, Maria Serena Roca, Maria Patrizia Stoppelli, Gennaro Ciliberto, Nunzia Simona Losito, Maria Vincenza Carriero   +13 more
doaj   +1 more source

The number of subsets of integers with no $k$-term arithmetic progression [PDF]

, 2016
Addressing a question of Cameron and Erd\Ho s, we show that, for infinitely many values of $n$, the number of subsets of $\{1,2,\ldots, n\}$ that do not contain a $k$-term arithmetic progression is at most $2^{O(r_k(n))}$, where $r_k(n)$ is the maximum ...
Balogh, József, Liu, Hong, Sharifzadeh, Maryam   +2 more
core   +2 more sources

DPVis: Visual Analytics with Hidden Markov Models for Disease Progression Pathways

, 2020
Clinical researchers use disease progression models to understand patient status and characterize progression patterns from longitudinal health records.
Anand, Vibha,, Frohnert, Brigitte I.,, Ghosh, Soumya,, Kwon, Bum Chul,, Lund University., Lund University., Lundgren, Markus,, Ng, Kenney,, Severson, Kristen A.,, Sun, Zhaonan,   +9 more
core   +1 more source

Is the tumor cell side of the immunological synapse a polarized secretory domain?

Frontiers in Immunology
The formation of a lytic immunological synapse (IS) is crucial for cytotoxic lymphocytes to accurately target and effectively eliminate malignant cells. While significant attention has been focused on the lymphocyte side of the IS, particularly its role ...
Andrea Michela Biolato, Andrea Michela Biolato, Liza Filali, Diogo Pereira Fernandes, Diogo Pereira Fernandes, Flora Moreau, Takouhie Mgrditchian, Céline Hoffmann, Céline Hoffmann, Clément Thomas   +9 more
doaj   +1 more source

Noninvasive Urinary Monitoring of Progression in IgA Nephropathy. [PDF]

, 2019
Standard methods for detecting and monitoring of IgA nephropathy (IgAN) have conventionally required kidney biopsies or suffer from poor sensitivity and specificity.
Fervenza, Fernando C, Lafayette, Richard A, Sarwal, Minnie M, Sarwal, Reuben D, Yang, Joshua YC   +4 more
core   +1 more source

E2F1 promotes cell migration in hepatocellular carcinoma via FNDC3B

FEBS Open Bio
FNDC3B (fibronectin type III domain containing 3B) is highly expressed in hepatocellular carcinoma (HCC) and other cancer types, and fusion genes involving FNDC3B have been identified in HCC and leukemia.
Kate Hua, Chen‐Tang Wu, Chin‐Hui Lin, Chian‐Feng Chen   +3 more
doaj   +1 more source

Communication and Language Profiles of Children Treated for Posterior Fossa Brain Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cognitive and language deficits are frequently reported sequelae of posterior fossa brain tumors (PFBT). Typically, delayed onset impedes prompt assessment and early intervention. This has devastating implications for quality of life.
Zara Sved, Meghan Hesse, Jennie Cusiter, Annabel Webb, Kimberley Docking   +4 more
wiley   +1 more source

Microsatellite instability and mismatch repair deficiency in bladder urothelial carcinoma: a Tunisian single-center study

Journal of the Egyptian National Cancer Institute
Background Microsatellite instability (MSI) and deficiency in the human mismatch repair (MMR) system are critical drivers of genomic instability in various cancers.
Ahlem Bdioui, Mariem Akkari, Maroua Krifa, Yosra Souiden, Ethmane Sleimane, Wafa Mokni, Nada Ben Lazrek, Sarra Mestiri, Sihem Hmissa, Nabiha Missaoui   +9 more
doaj   +1 more source