Results 51 to 60 of about 2,483,222 (269)
Frontiers in Genetics, 2019 The acknowledgment that pollutants might influence the epigenome raises serious concerns regarding their long-term impact on the development of chronic diseases. The herbicide glyphosate has been scrutinized for an impact on cancer incidence, but reports
Manon Duforestel +32 more
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N6-Adenosine Methylation of miRNA-200b-3p Influences Its Functionality and Is a Theranostic Tool
Molecular Therapy: Nucleic Acids, 2020 MicroRNAs (miRNAs or miRs) play crucial roles in biological and pathological processes. Some miRNAs also appear as promising biomarkers and therapeutic tools. However, the epitranscriptomic regulation of miRNAs is not yet fully elucidated in all of their
Joséphine Briand +7 more
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Nature Communications, 2022 Stomatin is a component of lipid rafts. Here, Wu et al. show that stomatin modulates the differentiation and functions of adipocytes by regulating adipogenesis signaling and fatty acid influx such that with excessive calorie intake, increased stomatin ...
Shao-Chin Wu +12 more
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Tyrosine phosphorylation of lamin A by Src promotes disassembly of nuclear lamina in interphase
Life Science Alliance, 2021 Phosphorylation of lamin A at tyrosine residue 45 by Src has an adverse effect on the assembly of nuclear lamina, which may be involved in nuclear dysmorphia, genomic instability, and nuclear plasticity in interphase.
Ching-Tung Chu +3 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei +17 more
wiley +1 more source
Less but Better? Teaching Maths in Further Education and Collateral Growth
Education Sciences, 2020 The paper presents and explores the experience of maths students studying in a context shaped by a core concept maths curriculum. The three vignettes that illuminate experience are drawn from a larger research project that worked with five teachers and ...
Lawrence Nixon, John B. Cooper
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Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
Pediatric Blood &Cancer, EarlyView.ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
How sports application functions promote college students’ exercise behavior: a mixed-methods study
Humanities & Social Sciences CommunicationsThis study explores how sports and fitness application functions influence college students’ physical exercise behavior, focusing on three core dimensions: system quality, information quality, and service quality.
Cheng Qiu, Chong Zhang, Yao Yin
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The effect of metformin on the survival of colorectal cancer patients with type 2 diabetes mellitus
Scientific Reports, 2022 Evidence from previous studies suggests a protective effect of metformin in patients with colorectal cancer (CRC). The aim of this study was to examine the associations between metformin use and overall survival (OS) and disease-free survival (DFS) in ...
Zeinab Tarhini +5 more
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The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source