Results 101 to 110 of about 6,463,095 (311)

Isatuximab, pomalidomide and dexamethasone in the treatment of relapsed/refractory multiple myeloma in real clinical practice [PDF]

Терапевтический архив
Aim. To evaluate the efficacy and tolerability of the combination of isatuximab, pomalidomide, dexamethasone (IsaPd) in the treatment of relapsed refractory multiple myeloma (RRMM) in a real clinical practice. Materials and methods.
Vadim V. Ptushkin, Yulia В. Kochkareva, Ekaterina А. Sukhova, Eugene A. Nikitin   +3 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Prognostic significance of circulating tumor DNA detection and quantification in cervical cancer: a systematic review and meta-analysis

Frontiers in Oncology
BackgroundCirculating tumor DNA (ctDNA) is an emerging biomarker in cervical cancer, with elevated levels typically indicating a higher tumor burden. However, its prognostic value in cervical cancer patients remains debated.
Xiumin Zhao, Shufu Hou, Ruiqi Hao, Yelei Zang, Dandan Song   +4 more
doaj   +1 more source

Recursive partitioning models for overall survival and progression-free survival.

, 2018
For overall survival, recursive partitioning allowed stratification of patients into five prognostic classes (A). Overall survival was well-stratified based on RPA class (B); log-rank p < 0.01.
Johnny Kao (154784), Diandra N. Ayala-Peacock (5094854), Jason Lee (1330398), Michael T. Milano (5094851), Max W. Sung (155300), Joseph K. Salama (192313), Julian C. Hong (5094857), Paul Okunieff (302426), James J. Urbanic (5094845), Steven J. Chmura (113286), Ralph R. Weichselbaum (113294), A. William Blackstock (5094848)   +11 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Univariate analysis of progression free survival and overall survival.

, 2016
Univariate analysis of progression free survival and overall survival.
Su Woon Kim (2212930), Balram Chowbay (110465), Ravindran Kanesvaran (780162), Chong Hee Lim (294673), Tina Koh (2212933), Swee Peng Yap (2212924), Quan Sing Ng (780165), Lynette Oon (2212891), Kiat Hon Lim (593520), Chian Min Loo (2212918), Wan Teck Lim (2212903), Anantham Devanand (2212906), Anne Ann Ling Hsu (2212927), Heng Nung Koong (2212936), Cindy Lim (2212915), Daniel Shao Weng Tan (2212921), Mei Kim Ang (381290), Eng Huat Tan (2212939), Amit Jain (2183937), Angela Takano (2212900), Wu Meng Tan (2212909), Eugene MingJin Gan (2212912), Kian Sing Chan (2212894), Chee Keong Toh (780164), Kam Weng Fong (2212942), David Zhihao Ng (2212897)   +25 more
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Progression-free survival among patients categorized into 4 groups according to radiotherapy dose and clinical target volume (CTV) margin.

, 2018
Progression-free survival among patients categorized into 4 groups according to radiotherapy dose and clinical target volume (CTV) margin.
Seo Hee Choi (2609779), Chang-Ok Suh (2609776), Sang Kyum Kim (475627), Kyoo-Ho Shin (3578543), Seung Hyun Kim (354159), Hong In Yoon (748799)   +5 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Pre-Existing Diabetes Limits Survival Rate After Immune Checkpoint Inhibitor Treatment for Advanced Lung Cancer: A Retrospective Study in Japan [Corrigendum]

Diabetes, Metabolic Syndrome and Obesity, 2021
Hisanaga K, Uchino H, Kakisu N, et al. Diabetes Metab Syndr Obes. 2021;14:773—781. Page 775, left column, third paragraph, line 4, the text “(p<0.5)” should read “(p<0.05)”.
Hisanaga K, Uchino H, Kakisu N, Miyagi M, Yoshikawa F, Sato G, Isobe K, Kishi K, Homma S, Hirose T   +9 more
doaj