Results 11 to 20 of about 20,462 (241)

”Shrimp sign” in progressive multifocal leukoencephalopathy [PDF]

open access: yesAnnals of Indian Academy of Neurology
Ayush Agarwal   +3 more
doaj   +2 more sources

The still under-investigated role of cognitive deficits in PML diagnosis [PDF]

open access: yes, 2017
Background: Despite cognitive deficits frequently represent the first clinical manifestations of Progressive Multifocal Leukoencephalopathy (PML) in Natalizumab-treated MS patients, the importance of cognitive deficits in PML diagnosis is still under ...
Amato, Maria Pia   +49 more
core   +4 more sources

Progressive Multifocal Leukoencephalopathy [PDF]

open access: yesF1000Research, 2015
Progressive multifocal leukoencephalopathy (PML) is a devastating demyelinating disease with significant morbidity and mortality and no effective, targeted therapies. It is most often observed in association with abnormalities of cell-mediated immunity, in particular human immunodeficiency virus (HIV) infection, but also occurs in association with ...
Adang, Laura, Berger, Joseph
openaire   +3 more sources

A case of progressive multifocal leukoencephalopathy in a post-kidney transplant patient with improvement after discontinuation of immunosuppressive drugs and combination therapy with mefloquine and mirtazapine

open access: yesRenal Replacement Therapy, 2023
Background Progressive multifocal leukoencephalopathy is a rare disease, but the prognosis is very poor, especially in the immunosuppressed state with a non-HIV background, and there is no established treatment.
Neri Sone   +13 more
doaj   +1 more source

AIDS-related progressive multifocal leukoencephalopathy

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2020
INTRODUCTION: Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV).
Carolina de Oliveira Abrão   +5 more
doaj   +1 more source

Atezolizumab Treatment for Progressive Multifocal Leukoencephalopathy

open access: yesEmerging Infectious Diseases, 2022
Atezolizumab successfully reinvigorated JC virus immunity in a patient in Belgium with progressive multifocal leukoencephalopathy, as demonstrated by clinical, virologic, and radiologic response to treatment.
Nicolas Lambert   +4 more
doaj   +1 more source

Natalizumab affects T-cell phenotype in multiple sclerosis: implications for JCV reactivation [PDF]

open access: yes, 2016
The anti-CD49d monoclonal antibody natalizumab is currently an effective therapy against the relapsing-remitting form of multiple sclerosis (RRMS). Natalizumab therapeutic efficacy is limited by the reactivation of the John Cunningham polyomavirus (JCV ...
A Bellizzi   +51 more
core   +6 more sources

Clinical and Radiological Characterization of Progressive Multifocal Leukoencephalopathy in HIV-Infected Patients: A Retrospective Analysis and Review of the Literature

open access: yesActa Médica Portuguesa, 2015
Introduction: Progressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by John Cunningham virus, mostly associated with immunodeficiency conditions, such as the human immunodeficiency virus infection ...
Luís Augusto   +4 more
doaj   +1 more source

JC Polyomavirus, progressive multifocal leukoencephalopathy and immune reconstitution inflammatory syndrome: a review

open access: yesAIDS Research and Therapy, 2020
The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individuals.
Vijay Harypursat   +3 more
doaj   +1 more source

Case report of a patient with progressive multifocal leukoencephalopathy under treatment with dimethyl fumarate [PDF]

open access: yes, 2015
BACKGROUND: Progressive multifocal leukoencephalopathy is a severe demyelinating disease caused by the polyoma JC virus in patients with reduced immunocompetence.
Antje Bornemann   +4 more
core   +1 more source

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