Results 121 to 130 of about 5,151 (175)

Virus-Specific T Cells and Response to Checkpoint Inhibitors in Progressive Multifocal Leukoencephalopathy.

JAMA Neurol
Möhn N, Grote-Levi L, Bonifacius A, Tischer-Zimmermann S, Nay S, Jendretzky KF, Sassmann ML, Karacondi K, Zent M, Konen FF, Sühs KW, Meuth SG, Pawlitzki M, Warnke C, Ayzenberg I, Schneider R, Helmchen C, Brüggemann N, Klebe S, Hildner M, Grefkes C, Nitsch L, Hühnchen P, Böltz S, Alt L, Tumani H, Kleinschnitz C, Pul R, Grauer O, Clifford D, Gnanapavan S, Wicklein R, Perpoint T, Beudel M, Del Bello A, Rauer S, Wiendl H, Jelcic I, Gasnault J, Cimini E, Antinori A, Pinnetti C, Pourcher V, Weiss N, Lambert N, Maecker-Kolhoff B, Höglinger GU, Zahraeifard S, Cortese I, Eiz-Vesper B, Martin-Blondel G, Skripuletz T, Immunotherapy for PML Study Group.   +52 more
europepmc   +1 more source

Progressive multifocal leukoencephalopathy (PML)

Clinical Neurology, 2011
Progressive multifocal leukoencephalopathy (PML) is caused by reactivation of latently infected JCV when hosts' immune system is impaired by HIV infection, hematologic diseases, collagen diseases, immunemodulatory therapy and so on. PML was rare but HIV infection and Natalizumab have made it much more common while the prognosis is much better than ...
Masayuki Saijo, Hiroaki Yokote, Yukiko Shishido-Hara   +2 more
exaly   +4 more sources

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The emergence of progressive multifocal leukoencephalopathy (PML) in rheumatic diseases

Journal of Autoimmunity, 2008
Progressive multifocal leukoencephalopathy (PML) is a rare and devastating neurological disease with areas of demyelination in the central nervous system classically associated with profound imunosuppression. PML is caused by reactivation of latent JC virus, leading to the death of myelin-producing oligodendrocytes typically with a rapidly fatal ...
Merrill Eric Gershwin, Aftab A. Ansari, Gurtej S Cheema   +2 more
exaly   +3 more sources

Progressive Multifocal Leukoencephalopathy (PML)

2014
Progressive multifocal leukoencephalopathy (PML) was first considered a distinct neurological entity in 1958. Its neuropathology is represented by multifocal demyelinating lesions accompanying oligodendroglia-like cells with markedly enlarged nuclei. Electron microscopy in 1965 showed polyomavirus-like structures in the enlarged nuclei.
exaly   +2 more sources

Spontaneous progressive multifocal leukoencephalopathy (PML) in macaques

Nature, 1975
PROGRESSIVE multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system (CNS) which has so far been recognised only in man1,2. Although it is an infrequent cause of clinical neurological disorder3, it is of particular interest because of its frequent association with diseases in which immunological competence is ...
D H, Gribble, C C, Haden, L W, Schwartz, R V, Henrickson   +3 more
openaire   +2 more sources

Are astrocytes infected in progressive multifocal leukoencephalopathy (PML)?

Acta Neuropathologica, 1982
Ultrastructural characteristics of the early steps of PML virus infection, i.e. adsorption, penetration, and intracellular virus transport were demonstrated in astrocytes. These phenomena were more frequently seen in the cytoplasm than virus assembly in the nuclei. Infection of the astrocytes is usually non-productive.
M, Mázló, I, Tariska
openaire   +2 more sources

Progressive multifocal leukoencephalopathy (PML). A case report and review of literature.

Medicine in Evolution, 2020
Progressive multifocal leukoencephalopathy (PML) is a disease that produces neural demyelination in the central nervous system caused by reactivation of a DNA virus that remains dormant in immunocompetent individuals, known as John Cunningham virus (JCV) occasioned by a prior HIV infection with immunosuppression.
M. Stoian, S.M. Erscoiu, P.I. Calistru
openaire   +1 more source

Progressive multifocal leukoencephalopathy (PML)

Neurology, 1980
Cell-mediated immunity was studied by in vitro tests in seven patients with progressive multifocal leukoencephalopathy (PML). Lymphocyte proliferation in response to mitogenic stimulation was reduced to a variable degree in all patients, indicating a general impairment of cell-mediated immune responsiveness, although mitogen-induced production of the ...
E, Willoughby, R W, Price, B L, Padgett, D L, Walker, B, Dupont   +4 more
openaire   +2 more sources

AIDS‐associated progressive multifocal leukoencephalopathy (PML)

Neurology, 1990
We studied brain sections from 10 patients with the acquired immunodeficiency syndrome (AIDS) and progressive multifocal leukoencephalopathy (PML) by in situ hybridization with a biotin-labeled JC virus (JCV) DNA probe and by immunohistochemistry using antibody against the JCV capsid antigen.
A J, Aksamit, H E, Gendelman, J M, Orenstein, G H, Pezeshkpour   +3 more
openaire   +2 more sources

Treatment of progressive multifocal leukoencephalopathy (PML) with cidofovir in an AIDS patient

Antiviral Research, 1996
info:eu-repo/semantics ...
Snoeck, Robert, De Wit, Stéphane, Rossi, Camelia, Dachy, Bernard, O'Doherty, Elizabeth, Naessens, L., Balzarini, Jan, De Clerc, E., Goldman, Serge, Clumeck, Nathan   +9 more
openaire   +3 more sources