Results 111 to 120 of about 8,307 (217)

Natalizumab therapy, 2013 [PDF]

, 2014
Multiple sclerosis (MS) is the most common chronic disease of the central nervous system in young adults. No curative therapy is known. Currently, six drugs are available that can reduce the activity of MS.
Bencsik, Krisztina, Karácsony, M., Vécsei, László   +2 more
core  

B Cell Therapies, Approved and Emerging: a Review of Infectious Risk and Prevention During Use [PDF]

, 2015
The development of B cell-targeted biologics represents a major advance in the treatment of autoimmune rheumatic diseases. As with other immunosuppressive agents, risk of infection is a key clinical concern.
Buch, MH, Md Yusof, MY, Vital, EM
core   +1 more source

Diagnostic difficulties in progressive multifocal leukoencephalopathy: a case report

Folia Neuropathologica
Progressive multifocal leukoencephalopathy (PML) is a demyelination disease of the central nervous system (CNS) caused by viral infection with John Cunningham polyomavirus (JC virus, JCV). PML affects mainly patients with immunodeficiency.
Angelika Stapińska-Syniec, Michał Sobstyl, Katarzyna Kurowska, Albert Acewicz, Teresa Wierzba-Bobrowicz   +4 more
doaj   +1 more source

Progressive Multifocal Leukoencephalopathy in a Young Male With Concurrent Neurosyphilis and HIV Infection: A Case Report

Journal of the International Association of Providers of AIDS Care
Background The co-infection of human immunodeficiency virus (HIV) and neurosyphilis presents a significant clinical challenge due to the increased risk of opportunistic infections, including progressive multifocal leukoencephalopathy (PML).
Chunyan Zhang MD, PhD, Lijun Cao MD, Rulin Mi MD   +2 more
doaj   +1 more source

A case report of simultaneous PML-IRIS during corticosteroids tapering in a patient with an anti-synthetase syndrome [v1; ref status: indexed, http://f1000r.es/2l6]

F1000Research, 2013
We report a case of simultaneous progressive multifocal leukoencephalopathy-associated immune reconstitution inflammatory syndrome (PML-IRIS) during corticosteroid tapering in a patient with an anti-synthetase syndrome.
Guillaume Martin-Blondel, David Brassat, Hervé Dumas, Emmanuelle Uro-Coste, Daniel Adoue, Hans Lassmann, Michel Clanet   +6 more
doaj   +1 more source

Incidence and Outcome of Progressive Multifocal Leukoencephalopathy over 20 Years of the Swiss HIV Cohort Study [PDF]

, 2017
Background. We investigated the incidence and outcome of progressive multifocal leukoencephalopathy (PML) in human immunodeficiency virus (HIV)-infected individuals before and after the introduction of combination antiretroviral therapy (cART) in 1996 ...
Battegay, Manuel, Bernasconi, Enos, Cavassini, Matthias, Elzi, Luigia, Fux, Christoph A., Garzoni, Christian, Hirsch, Hans H., Khanna, Nina, Mueller, Nicolas J., Vernazza, Pietro   +9 more
core  

Progressive multifocal leukoencephalopathy restricted to the posterior fossa in a patient with systemic lupus erythematosus

Brazilian Journal of Infectious Diseases
Progressive multifocal leukoencephalopathy is a neurological infectious disease caused by the John Cunningham polyomavirus (JCV), an opportunistic agent with worldwide distribution.
Fabrício Guimarães Gonçalves, Leslie Lamb, Raquel Del Carpio-O'Donovan   +2 more
doaj   +1 more source

Relapsing-remitting multiple sclerosis: advances in disease-modifying therapies [PDF]

, 2015
Multiple sclerosis is a demyelinating disease affecting the central nervous system. It is the most prevalent disabling neurological condition among young adults, with onset typically between 20 and 40 years of age. Infiltrating immune cells and microglia
Kay, Kathleen Alexandra
core   +1 more source

Poster Sessions

HemaSphere, Volume 9, Issue S1, June 2025.
wiley   +1 more source

SF2/ASF binding region within JC virus NCCR limits early gene transcription in glial cells [PDF]

, 2013

core   +1 more source