Results 91 to 100 of about 8,307 (217)

Progressive multifocal leukoencephalopathy in a 27-year-old lady with systemic lupus erythematosus – rheumatoid arthritis overlap syndrome

Journal of the Formosan Medical Association, 2019
Progressive multifocal leukoencephalopathy (PML) is a rare viral demyelinating disease of central nervous system. Immunosuppression is a significant risk factor for the disease.
Chiao-Feng Cheng, Jen-Jen Su, Ya-Fang Chen, Yen-Chun Lin, Yi-Min Huang, Ko-Jen Li   +5 more
doaj   +1 more source

Predictors of Radiological and Clinical Disease Reactivation in Multiple Sclerosis Patients After Cessation of Natalizumab (Tysabri)

Brain and Behavior, Volume 15, Issue 9, September 2025.
This retrospective single‐center study looks at the frequency and degree of reactivation of disease following discontinuation of natalizumab in Lebanese patients with relapsing‐remitting multiple sclerosis, highlighting importance of early initiation of bridging disease‐modifying therapy.
Roba El Zibaoui, Nabil K. El Ayoubi, Samia J. Khoury   +2 more
wiley   +1 more source

Sphingosine‐1‐Phosphate Receptor Modulators for the Treatment of Ulcerative Colitis: A Narrative Review Focusing on Safety

United European Gastroenterology Journal, Volume 13, Issue 7, Page 1077-1091, September 2025.
ABSTRACT Ulcerative colitis is a chronic immune‐mediated inflammatory disease of the colon that causes considerable morbidity and increases the risk of colorectal cancer. Several targeted therapies have been developed for moderate‐to‐severe ulcerative colitis, significantly improving its management.
Massimo C. Fantini, Diego Centonze, Giovanni Giacobazzi, Silvia Benemei, Emanuele Romeo   +4 more
wiley   +1 more source

Beyond Uremia: Chronic Kidney Disease as a Cryptic Gateway for Opportunistic Neuroinvasion by John Cunningham Virus

Annals of Internal Medicine: Clinical Cases
Progressive multifocal leukoencephalopathy (PML), a devastating demyelinating central nervous system infection caused by John Cunningham virus (JCV) reactivation, typically occurs in profound immunosuppression.
Ethar Salman, Kalyan K. Shastri
doaj   +1 more source

A Representative Survey of M.S. Patients on Attitudes toward the Benefits and Risks of Drug Therapy [PDF]

, 2006
Background: Although M.S. patients face significant trade-offs between risks and benefits of drug therapy, little is known of their attitudes toward these risks and benefits.
John E. Calfee
core  

IBD 2024: Charting a New Course in IBD Proceedings of the Takeda Symposium 22–23 November 2024 W Hotel, Brisbane, Queensland, Australia

Journal of Gastroenterology and Hepatology, Volume 40, Issue S3, Page 3-22, September 2025.
ABSTRACT The symposium IBD 2024: Charting a New Course in IBD was held in Brisbane, Australia, in November 2024. This was the fifth such meeting for the Australian inflammatory bowel disease (IBD) healthcare community. This symposium provided an overview of current and emerging management strategies for ulcerative colitis (UC) and Crohn's disease (CD).
Uma Mahadevan, Vipul Jairath, Jakob Begun, Aviv Pudipeddi, Mayur Garg, Peter De Cruz, Christopher F. D. Li Wai Suen, Matthew C. Choy, Danny Con, Rose Vaughan, John D. Chetwood, David A. Clark, Craig Haifer, Miles P. Sparrow, Rupert Leong, Réme Mountifield   +15 more
wiley   +1 more source

Plasma microRNA Signature as Predictive Marker of Clinical Response to Therapy During Multiple Sclerosis

Annals of Clinical and Translational Neurology, Volume 12, Issue 8, Page 1595-1607, August 2025.
ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone, Alessandra Colamatteo, Teresa Micillo, Gianmarco Abbadessa, Silvia Garavelli, Clorinda Fusco, Claudia Russo, Francesco Perna, Federica Garziano, Claudia La Rocca, Maria Mottola, Giorgia Teresa Maniscalco, Simona Bonavita, Antonio Luca Spiezia, Alessia Castiello, Roberta Lanzillo, Vincenzo Brescia Morra, Claudio Procaccini, Paola de Candia, Giuseppe Matarese   +19 more
wiley   +1 more source

Treating Progressive Multifocal Leukoencephalopathy With Interleukin 7 and Vaccination With JC Virus Capsid Protein VP1 [PDF]

, 2017
Progressive multifocal leukoencephalopathy is a currently untreatable infection of the brain. Here, we demonstrate in 2 patients that treatment with interleukin 7, JC polyomavirus (JCV) capsid protein VP1, and a Toll-like receptor 7 agonist used as ...
Bofill-Mas, Silvia, Cinque, Paola, Croughs, Therese, Demina, Viktoria, Garcea, Robert, Girones, Rosina, Jelcic, Ilijas, Martin, Roland, Planas, Raquel, Schippling, Sven, Sospedra, Mireia, Stellmann, Jan-Patrick, Yousef, Sara   +12 more
core  

Spectrum of Neurologic Complications in Chronic Lymphocytic Leukemia [PDF]

, 2012
Neurologic disease is believed to be an unusual complication during the course of chronic lymphocytic leukemia. Nevertheless, it has already been proven in autopsy series that the incidence of occult nervous system infiltration is much higher than was ...
Lopes Silva, R
core   +1 more source

The future of multiple sclerosis treatments [PDF]

, 2016
Introduction. There are not many conditions in which the last few decades have brought such a major change in the landscape of treatments as is the case of multiple sclerosis (MS).
Agency EM, Amor S, Ayzenberg I, Beutler E, Bloomgren G, Cadavid D., Catalina Coclitu, Cris S. Constantinescu, Federation MSI, Fritz RB, Gonzalez-Cabrera PJ, Hartung HP, Hauser SCG, Johns TG, Johnson KP, McGuigan C, Munzel EJ, Pirko I, Radu Tanasescu, Rodgers JM, Sweetser MT, Tanasescu R, Tourbah A, Tuohy VK, Zhornitsky S   +24 more
core   +2 more sources