Results 71 to 80 of about 8,307 (217)

A case of Progressive Multifocal Leukoencephalopathy in a HIV patient

Journal of Clinical and Biomedical Sciences, 2022
Progressive Multifocal Leukoencephalopathy is a demyelinating disease of the brain which occurs as a result of reactivation of JC (John Cunningham) virus.
. Aashish, Anil Kumar Sakalecha, Ravindra Naik, A Chaithanya , G R Varshitha , R B Revanth   +5 more
doaj   +1 more source

Concomitant granule cell neuronopathy in patients with natalizumab-associated PML [PDF]

, 2016
Granule cell neuronopathy (GCN) is a rare JC virus infection of the cerebellar granule cell neurons in immunocompromised patients. On brain imaging, GCN is characterized by cerebellar atrophy which can be accompanied by infratentorial white matter ...
Eijk, J.J.J. (Jeroen) van, Killestein, J. (Joep), Siepman, D.A.M. (Dorine), Wattjes, M.P. (Mike P.), Wijburg, M.T. (Martijn T.)   +4 more
core   +1 more source

Efficacy and Safety of Rituximab Versus Inebilizumab in Patients With Neuromyelitis Optica Spectrum Disorder: A Dual‐Center, Real‐World Cohort Study

European Journal of Neurology, Volume 33, Issue 3, March 2026.
In our real‐world study of 276 patients, rituximab and inebilizumab demonstrated comparable efficacy in the medium term but differed in their safety profiles, with a significantly higher incidence of infusion‐related reactions observed in the rituximab group.
Ying Cui, Zihao Yu, Hengri Cong, Hao Zhang, Yutong Shi, Ai Guo, Yujing Li, Dongmei Jia, Chao Zhang, Kaibin Shi, Fu‐Dong Shi, Wei Jiang   +11 more
wiley   +1 more source

Progressive multifocal leukoencephalopathy in the clinical practice of a neurologist. Case report [PDF]

Consilium Medicum
Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection with severe brain damage caused by the JC-virus, against the background of immunosuppressive conditions.
Yuliana A. Belova, Sergey V. Kotov
doaj   +1 more source

Dynamic changes of mmp-9 plasma levels correlate with jvc reactivation and immune activation in natalizumab-treated multiple sclerosis patients [PDF]

, 2019
The aim of the study was to investigate the changes of matrix metalloproteinase (MMP)-2 and MMP-9 plasma levels during natalizumab treatment and their correlation with JC virus (JCV) reactivation and T-lymphocyte phenotypic modifications in peripheral ...
Ciardi, Maria Rosa, Cortese, Antonio, D’Agostino, Claudia, Francia, Ada, Frontoni, Marco, Iannetta, Marco, Latronico, Tiziana, Liuzzi, Grazia Maria, Mastroianni, Claudio Maria, Pati, Ilaria, Pietropaolo, Valeria, Pontecorvo, Simona, Prezioso, Carla, Vullo, Vincenzo, Zingaropoli, Maria Antonella   +14 more
core   +3 more sources

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

Annals of Clinical and Translational Neurology, Volume 13, Issue 1, Page 85-96, January 2026.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich, Tilman Schneider‐Hohendorf, Eric Baetscher, Evan L. Riddle, Marie Deffner, Emily Katsnelson, Janine Ferrant‐Orgettas, Julie Czerkowicz, John Anderson, Susan E. Goelz, Nicholas Schwab   +10 more
wiley   +1 more source

The pivotal image findings of progressive multifocal leukoencephalopathy: A case report

Tungs’ Medical Journal
Progressive multifocal leukoencephalopathy (PML) is a rare disease associated with the reactivation of the JC virus, particularly in immunocompromised patients.
Shou-De Ma, Chih-Wei Wei, Tai-Lin Huang, Chao-Hsin Wu, Shiang-Yu Chang   +4 more
doaj   +1 more source

AIDS-related progressive multifocal leukoencephalopathy

Revista da Sociedade Brasileira de Medicina Tropical, 2020
INTRODUCTION: Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV).
Carolina de Oliveira Abrão, Lissa Rodrigues Machado da Silva, Luiz Carlos Silva Souza, Nathalia de Mello Bisso, Marília Dalva Turchi, Adriana Oliveira Guilarde   +5 more
doaj   +1 more source

Safety and Effectiveness of Dimethyl Fumarate in Japanese Patients With Multiple Sclerosis: 2‐Year Post‐Marketing Surveillance Data

Neurology and Clinical Neuroscience, Volume 14, Issue 1, Page 54-68, January 2026.
ABSTRACT Background Dimethyl fumarate (DMF) is an orally administered disease‐modifying drug used for the treatment of multiple sclerosis (MS) in numerous countries worldwide. Aim An ongoing post‐marketing surveillance (PMS) is assessing the real‐world safety and effectiveness of DMF in Japanese patients with MS.
Hirofumi Ochi, Toshiyuki Fukazawa, Takashi Yamamura, Kazumasa Yokoyama, Takashi Ohashi, Ichiro Nakashima, Masanori Mizuno, Hikoaki Fukaura, Izumi Kawachi, Tatsusada Okuno, Ryusuke Sato, Haruki Makioka, Aya Tsuchiya, Michihiro Kanda, Yayoi Sato, Takahiko Saida   +15 more
wiley   +1 more source

Progressive multifocal leukoencephalopathy in HIV-infected patients: clinical features and diagnosis (literature review)

Журнал инфектологии, 2019
Progressive multifocal leukoencephalopathy (PML) is one of the most severe opportunistic diseases of the central nervous system, which leads to multiple demyelination of brain structures, neurological symptoms and frequent death or disability of the ...
E. A. Samotolkina, A. V. Pokrovskaya, S. V. Matosova, E. A. Domonova   +3 more
doaj   +1 more source