Results 61 to 70 of about 5,030 (173)

Beyond Uremia: Chronic Kidney Disease as a Cryptic Gateway for Opportunistic Neuroinvasion by John Cunningham Virus

Annals of Internal Medicine: Clinical Cases
Progressive multifocal leukoencephalopathy (PML), a devastating demyelinating central nervous system infection caused by John Cunningham virus (JCV) reactivation, typically occurs in profound immunosuppression.
Ethar Salman, Kalyan K. Shastri
doaj   +1 more source

Efficacy and Safety of Rituximab Versus Inebilizumab in Patients With Neuromyelitis Optica Spectrum Disorder: A Dual‐Center, Real‐World Cohort Study

European Journal of Neurology, Volume 33, Issue 3, March 2026.
In our real‐world study of 276 patients, rituximab and inebilizumab demonstrated comparable efficacy in the medium term but differed in their safety profiles, with a significantly higher incidence of infusion‐related reactions observed in the rituximab group.
Ying Cui, Zihao Yu, Hengri Cong, Hao Zhang, Yutong Shi, Ai Guo, Yujing Li, Dongmei Jia, Chao Zhang, Kaibin Shi, Fu‐Dong Shi, Wei Jiang   +11 more
wiley   +1 more source

Biopsy-proven progressive multifocal leukoencephalopathy in a renal transplant patient

Saudi Journal of Kidney Diseases and Transplantation, 2019
Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease that affects immunocompromised hosts. Most often the disease is reported in association with leukemia, lymphoma, and AIDS.
Pramod Kumar Guru, Megan B Vissing, Anjali Agarwal, Murli Krishna   +3 more
doaj   +1 more source

Hemianopia and visual loss due to progressive multifocal leukoencephalopathy in natalizumab-treated multiple sclerosis

Clinical Ophthalmology, 2012
Tina Rike Herold,1 Veronika Jakl,3 Anno Graser,4 Kirsten Eibl-Lindner1,21Department of Ophthalmology, 2Department of Ophthalmology, Campus Innenstadt, 3Department of Neurology, 4Department of Clinical Radiology, Campus Grosshadern, University of Munich ...
Herold TR, Jakl V, Graser A, Eibl-Lindner K   +3 more
doaj  

Case report: Progressive multifocal leukoencephalopathy co-occurring with neurosarcoidosis: early brain biopsy and appropriate therapy for PML resulted in a favorable prognosis

Frontiers in Immunology
Progressive multifocal leukoencephalopathy (PML) is a rare central nervous system disease caused by JC virus (JCV) infection. Human immunodeficiency virus (HIV) infection is the greatest risk factor for PML.
Qiannan Wang, Shintaro Tsuboguchi, Kouichirou Okamoto, Mari Tada, Akiyoshi Kakita, Kazuo Nakamichi, Makoto Oishi, Masato Kanazawa, Osamu Onodera   +8 more
doaj   +1 more source

Progressive multifocal leukoencephalopathy: new concepts

Arquivos de Neuro-Psiquiatria, 2013
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the CNS caused by reactivation of JC virus (JCV) in a setting of cellular immunosuppression.
Marco A. Lima
doaj   +1 more source

Misdiagnosed Progressive Multifocal Leukoencephalopathy (PML) in an HIV-Negative Patient With Discoid Lupus: A Case Report. [PDF]

Cureus, 2023
Mousa A, Rashid MH, Arslan K, Lofrese CN, Najeeb N.   +4 more
europepmc   +1 more source

Long-term safety and efficacy of natalizumab in relapsing-remitting multiple sclerosis: impact on quality of life

Patient Related Outcome Measures, 2014
Raquel Planas, Roland Martin, Mireia Sospedra Neuroimmunology and MS Research, Department of Neurology, University of Zurich, Zurich, Switzerland Abstract: Natalizumab was the first monoclonal antibody to be approved for the treatment of relapsing ...
Planas R, Martin R, Sospedra M
doaj  

Progressive Multifocal Leukoencephalopathy in an Immunocompetent Taiwanese Patient

Journal of the Formosan Medical Association, 2007
Progressive multifocal leukoencephalopathy (PML) is a deadly demyelinating brain disease caused by JC virus (JCV). Genomic analysis of viral isolates in these cases often shows prototype-like JCV and its variants, which is a virulent strain compared to ...
Yung-Yee Chang, Min-Yu Lan, Cheng-Huei Peng, Hsiu-Shan Wu, DeChing Chang, Jia-Shou Liu   +5 more
doaj   +1 more source

Progressive multifocal leukoencephalopathy as a complication of disease-modifying treatment of multiple sclerosis

Анналы клинической и экспериментальной неврологии, 2018
The review provides modern understanding of the pathogenesis of progressive multifocal leukoencephalopathy (PML), a severe and potentially fatal form of multiple-lesion disorder of the brain white matter.
Maria N. Zakharova, Elena V. Lysogorskaia, Maria V. Ivanova, Ivan А. Kochergin, Yulia E. Korzhova   +4 more
doaj   +1 more source