Results 211 to 220 of about 5,411,820 (260)

Task-oriented virtual reality and brain functional plasticity in progressive multiple sclerosis: A randomized controlled trial on upper limb rehabilitation. [PDF]

Mult Scler
Hamedani M, Lombardi G, Boffa G, Pistarini C, Cossa FM, Capello E, Malucchi S, Anselmino A, Fiabane EM, Di Sapio A, Poirè I, Sciolla C, Calautti C, Incollu F, Spada F, Bertolotto A, Springhetti I, Nardone A, Sollazzo R, Fazio G, Galetti G, Sormani MP, Boghi A, Ponzano M, Inglese M, Cellerino M, Mancardi G.   +26 more
europepmc   +1 more source

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

A glial oxidative signature predicts disability in primary progressive multiple sclerosis and is associated with long-term cognitive decline. [PDF]

Front Immunol
Miguela A, Huertas-Pons JM, Coll-Martinez C, Gifreu-Fraixinó A, Salavedra-Pont J, Comabella M, Villar LM, Gich J, Álvarez-Bravo G, Ramió-Torrentà L, Quiroga-Varela A.   +10 more
europepmc   +1 more source

Prevalence of pregnancy and birth outcomes following biologic exposure in immune‐mediated inflammatory diseases: A population‐based study

British Journal of Clinical Pharmacology, EarlyView.
Aims Almost 5% of pregnancies are affected by immune‐mediated inflammatory diseases (IMIDs). As treatments become available, understanding their use during pregnancy is important. We aimed to describe maternal, pregnancy and infant outcomes among IMID pregnancies exposed to biologic therapies. Methods Using the Merative™ MarketScan® Commercial Database,
Leah K. Flatman, Lisiane F. Leal, Gabra Nohmie, Anick Bérard   +3 more
wiley   +1 more source

Optical Coherence Tomography Angiography Findings in Primary Progressive Multiple Sclerosis Patients Receiving Ocrelizumab Treatment. [PDF]

Diagnostics (Basel)
Çakır B, Kaplan Güngördü S, Özkan Aksoy N, Kotan D.   +3 more
europepmc   +1 more source

Mechanism study of an articular cartilage repair material and its forward‐looking test for space medicine

BMEMat, EarlyView.
The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu, Hang Yao, Zhen Zhang, Zhonglian Wu, Huiqun Zhou, Bangheng Liu, Liang Ma, Yulei Mu, Dong‐An Wang   +8 more
wiley   +1 more source

Correction: Efficacy and safety of mesenchymal stem cell transplantation for progressive multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials with clinical implications for patient stratification and treatment optimization. [PDF]

Front Immunol
Guo H, Zeng L, Sun L.
europepmc   +1 more source

Engineering programmable peptide hydrogels for chronic refractory wounds: A mechanism‐driven framework

BMEMat, EarlyView.
To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv, Xinyi Chao, Jiamin Zhang, Jianfeng Liu   +3 more
wiley   +1 more source

Hippocampal inflammation and depression in multiple sclerosis: integrating evidence from TSPO PET and resting state fMRI [PDF]

, 2015
Owen, D, Onega, M, Colasanti, A, Bishop, C, Nicholas, R, Wall, M, Young, AH, Newbould, RD, Muraro, P, Giannetti, P, Rabiner, EA, Gunn, R, Ciccarelli, O, Guo, Q, Matthews, PM, Malik, O, Piccini, P   +16 more
core  

When Subtle Guiding Catheter‐Induced Stent Deformation Leads to Abluminal Guidewire Passage: Successful IVUS Tip‐Detection‐Guided Bailout

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Incomplete stent apposition at the proximal coronary artery may predispose to subtle guiding catheter–induced stent deformation, creating a gap between the stent and the vessel wall that facilitates inadvertent abluminal guidewire passage. We report a case in which balloon dilatation over an unrecognized abluminal guidewire resulted in severe ...
Yuto Abe, Yuya Hirata, Fumimasa Tabata, Tomomi Koizumi   +3 more
wiley   +1 more source