Results 101 to 110 of about 33,332 (299)
Amantadine Can Treat Blepharospasm in Levodopa Peak‐Dose Dyskinesia
Movement Disorders Clinical Practice, EarlyView.
Francisco de Assis Aquino Gondim +4 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Objectives The aim was to evaluate the safety, tolerability, pharmacokinetics, and potential clinical efficacy of AZP2006, an oral pleiotropic drug modulating progranulin levels, in patients with progressive supranuclear palsy (PSP), a rare tauopathy. Methods A randomized, double‐blind, placebo‐controlled, parallel‐group trial was conducted at
Jean‐Christophe Corvol +17 more
wiley +1 more source
Apathy and impulsivity in frontotemporal lobar degeneration syndromes [PDF]
, 2017 Apathy and impulsivity are common and disabling consequences of frontotemporal lobar degeneration. They cause substantial carer distress, but their aetiology remains elusive.
Coyle-Gilchrist, ITS +8 more
core +3 more sources
A Biomarker‐Based Classification of Corticobasal Syndrome
Movement Disorders, EarlyView.Abstract Background Corticobasal syndrome (CBS) is a clinically defined syndrome with progressive movement and cortical dysfunction, caused by various underlying pathologies, most commonly tau‐predominant pathologies such as progressive supranuclear palsy and corticobasal degeneration, or Alzheimer's disease (AD).
Carla Palleis +13 more
wiley +1 more source
Annals of Indian Academy of Neurology, 2014 Aims: In progressive supranuclear palsy (PSP) tissue damage occurs in specific cortical and subcortical regions. Voxel based analysis using T1-weighted images depict quantitative gray matter (GM) atrophy changes.
Mangalore Sandhya +4 more
doaj +1 more source
Astrogliopathy predominates the earliest stage of corticobasal degeneration pathology. [PDF]
, 2016 Animal models have shown that tau seeding and propagation are strain- and neural network-specific. The study of preclinical cases is valuable to gain insights into early pathological features of corticobasal degeneration and its progression.
Davey, K +9 more
core +2 more sources
Analyzing the ‘Bradykinesia Complex’ in Parkinson's Disease
Movement Disorders, EarlyView.Abstract Background Bradykinesia is the hallmark sign of parkinsonism. We recently proposed redefining bradykinesia as a complex of motor abnormalities, each reflecting separate pathophysiological elements. Objective To analyze the ‘bradykinesia complex’ in Parkinson's disease (PD) and healthy elderly individuals.
Giulia Paparella +9 more
wiley +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Spasmodic dysphonia is a laryngeal dystonia that can present as adductor, abductor, or mixed types, with or without tremor. The etiology is not understood fully. Comprehensive evaluation is required to establish the diagnosis. Treatments include voice therapy, medications, botulinum toxin injection, laryngeal surgery, deep brain stimulation ...
Aaron J. Jaworek, Robert T. Sataloff
wiley +1 more source
Challenges with the differential diagnosis of progressive supranuclear palsy and Parkinson’s disease
Анналы клинической и экспериментальной неврологии, 2017 Progressive supranuclear palsy (PSP) is a severe old-age neurodegenerativedisease that is characterized by pronouncedclinical polymorphism and has different phenotypes.
R. V. Magzhanov +5 more
doaj +1 more source