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Clinical Approach to Progressive Supranuclear Palsy [PDF]

open access: yesJournal of Movement Disorders, 2016
Sixty years ago, Steele, Richardson and Olszewski designated progressive supranuclear palsy (PSP) as a new clinicopathological entity in their seminal paper. Since then, in addition to the classic Richardson’s syndrome (RS), different clinical phenotypic
Helen Ling
doaj   +5 more sources

Progressive supranuclear palsy: new concepts [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2010
Progressive supranuclear palsy (PSP) is a distinctive form of neurodegenerative disease which affects the brainstem and basal ganglia. Patients present supranuclear ophthalmoplegia, postural instability and mild dementia.
Orlando Graziani Povoas Barsottini   +3 more
doaj   +5 more sources

Clinical Conditions “Suggestive of Progressive Supranuclear Palsy”—Diagnostic Performance [PDF]

open access: yes, 2020
Background: The Movement Disorder Society diagnostic criteria for progressive supranuclear palsy introduced the diagnostic certainty level “suggestive of progressive supranuclear palsy” for clinical conditions with subtle signs, suggestive of the disease.
Arzberger, T. (T.)   +19 more
core   +4 more sources

Progressive supranuclear palsy

open access: yesHospital Medicine, 2003
Progressive supranuclear palsy, also known as Steele–Richardson–Olszewski syndrome, is an uncommon neurodegenerative parkinsonian disorder that starts in middle and late life, and is frequently misdiagnosed as Parkinson's disease. This review will cover the epidemiology, clinical picture, differential diagnosis and management of patients with ...
Douglas G. Cole, Nutan Sharma
  +5 more sources

Neuropsychiatric disturbances in atypical Parkinsonian disorders [PDF]

open access: yes, 2018
Multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD) are the most common atypical parkinsonisms. These disorders are characterized by varying combinations of autonomic, cerebellar and pyramidal system ...
Belvisi, Daniele   +6 more
core   +1 more source

Atypical parkinsonism: An Update. [PDF]

open access: yes, 2013
Purpose of review: This update discusses novel aspects on genetics, diagnosis, and treatments of atypical parkinsonism published over the past 2 years. Recent findings: A genome-wide association study identified new genetic risk factors for progressive ...
Hoeglinger, GU, Stamelou, M
core   +1 more source

9.4 T MR microscopy of the substantia nigra with pathological validation in controls and disease

open access: yesNeuroImage: Clinical, 2017
Background: The anatomy of the substantia nigra on conventional MRI is controversial. Even using histological techniques it is difficult to delineate with certainty from surrounding structures.
LA Massey   +12 more
doaj   +1 more source

Abnormal resting-state functional connectivity in progressive supranuclear palsy and corticobasal syndrome [PDF]

open access: yes, 2017
Background: Pathological and MRI-based evidence suggests that multiple brain structures are likely to be involved in functional disconnection between brain areas. Few studies have investigated resting-state functional connectivity (rsFC) in progressive
Berardelli, Alfredo   +9 more
core   +2 more sources

Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid. [PDF]

open access: yes, 2016
BackgroundClinical diagnosis of parkinsonian syndromes like Parkinson's disease (PD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) is hampered by overlapping symptomatology and lack of diagnostic biomarkers, and definitive ...
Boman, Andrea   +8 more
core   +1 more source

Plasma metabolite biomarkers for multiple system atrophy and progressive supranuclear palsy.

open access: yesPLoS ONE, 2019
Radiological biomarkers have been reported for multiple system atrophy and progressive supranuclear palsy, but serum/plasma biomarkers for each disorder have not been established.
Akio Mori   +10 more
doaj   +1 more source

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