Patients with Parkinson′s disease are at risk of developing aspiration pneumonia. Pulmonary embolism is a rare but life-threatening complication in such patients, but could the same be true in progressive supranuclear palsy, an atypical form of ...
Robin G Manappallil, Vinod Krishnan
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Environmental Risk Factors for Progressive Supranuclear Palsy [PDF]
Typically, progressive supranuclear palsy (PSP) is clinically characterized by slow vertical saccades or supranuclear gaze palsy, levodopa-resistant parkinsonism with predominant axial symptoms, and cognitive executive impairment.
Hee Kyung Park +2 more
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Zolpidem in Progressive Supranuclear Palsy
Progressive supranuclear palsy (PSP) is a progressive neurodegenerative disorder, characterized by motor symptoms, postural instability, personality changes, and cognitive impairment. There is no effective treatment for this disorder.
Sandip K. Dash
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Elevated Levels of Methylmalonate and Homocysteine in Parkinson's Disease, Progressive Supranuclear Palsy and Amyotrophic Lateral Sclerosis [PDF]
Background/Aims: Increasing evidence suggests that elevated levels of homocysteine (Hcy) and methylmalonate (MMA) may be involved in the pathogenesis of neurodegenerative diseases. Methods: The urine levels of MMA and serum levels of Hcy as well as folic
Bötzel, Kai +4 more
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Identification of multiple system atrophy mimicking Parkinson's disease or progressive supranuclear palsy [PDF]
WWe studied a subset of patients with autopsy-confirmed multiple system atrophy who presented a clinical picture that closely resembled either Parkinson’s disease or progressive supranuclear palsy.
Asi, YT +15 more
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Criteria for the diagnosis of corticobasal degeneration [PDF]
Current criteria for the clinical diagnosis of pathologically confirmed corticobasal degeneration (CBD) no longer reflect the expanding understanding of this disease and its clinicopathologic correlations.
Armstrong, Melissa J +19 more
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Procerus sign: Mechanism, clinical usefulness, and controversies
This sign is observed in atypical parkinsonism mainly in Progressive Supranuclear Palsy. The exact mechanism of this sign is not clear but the contraction of the Corrugator Supercilii muscle is the most important factor for the generation of vertical ...
Shakya Bhattacharjee
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Corticobasal syndrome: neuroimaging and neurophysiological advances [PDF]
Corticobasal degeneration (CBD) is a neurodegenerative condition characterized by 4R-tau protein deposition in several brain regions that clinically manifests itself as a heterogeneous atypical parkinsonism typically expressing in the adulthood.
Asci, Francesco +9 more
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Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer. [PDF]
We report the case of a 75-year-old ex-professional boxer who developed diplopia and eye movement abnormalities in his 60's followed by memory impairment, low mood and recurrent falls.
Hardy, J +8 more
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Uncovering spatiotemporal patterns of atrophy in progressive supranuclear palsy using unsupervised machine learning [PDF]
To better understand the pathological and phenotypic heterogeneity of progressive supranuclear palsy and the links between the two, we applied a novel unsupervised machine learning algorithm (Subtype and Stage Inference) to the largest MRI data set to ...
Alexander, Daniel C +15 more
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