Drug resistance mediating Plasmodium falciparum polymorphisms and clinical presentations of parasitaemic children in Uganda. [PDF]
BackgroundPlasmodium falciparum genetic polymorphisms that mediate altered drug sensitivity may impact upon virulence. In a cross-sectional study, Ugandan children with infections mutant at pfcrt K76T, pfmdr1 N86Y, or pfmdr1 D1246Y had about one-fourth ...
Arinaitwe, Emmanuel +8 more
core +1 more source
Malaria prevention in travelling children
Preventing malaria in children is often neglected. Prevention is very important, as malaria is still a significant cause of childhood mortality. Parents must be aware that the same measures must be taken by children to avoid being bitten by mosquitoes ...
S. Mathijs
doaj +1 more source
Artemether-Lumefantrine Treatment Failure despite adequate lumefantrine day 7 Concentration in a Traveller with Plasmodium Falciparum Malaria after Returning from Tanzania. [PDF]
Artemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa.
Färnert, Anna +6 more
core
Background Malaria continues to be amongst the most frequent infectious diseases imported to Europe. Whilst European treatment guidelines are based on data from studies carried out in endemic areas, there is a paucity of original prospective treatment ...
Bouchaud Olivier +18 more
doaj +1 more source
Intravenous artesunate therapy is the first-line therapy for severe malaria, and is highly efficacious when used in combination with an oral partner drug such as doxycycline or atovaquone-proguanil.
Wilson W Chan +2 more
doaj +1 more source
The management and treatment of malaria [PDF]
Falciparum malaria can create severe complications. Antimalarial drugs such as quinine or chloroquine help in the treatment and management to these complications. The use of chemoprophylaxis is a must for persons travelling abroad to countries subject to
Gilles, Herbert M.
core
Fumagillin, an efficacious drug against renal sphaerosporosis of the common carp Cyprinus carpio [PDF]
At present no reliable and efficacious drugs are available for treating fish diseases caused by myxosporeans. By feeding Fumagillin DCH salt in the diet, the authors achieved very promising results in controlling renal sphaerosporosis, one of the ...
Baska, Ferenc +2 more
core
Production and characterization of different types of malaria pigment (hemozoin) and their potential use for screening for hemozoin inhibiting drugs [PDF]
Tese de mestrado. Biologia (Microbiologia Aplicada). Universidade de Lisboa, Faculdade de Ciências, 2012Malarial pigment, hemozoin, appears to modulate the immune system, however it remains controversial if it has stimulatory or inhibitory effects ...
Góis, Ana Margarida Ferreira, 1988-
core
Chaturaka Rodrigo,1 Senaka Rajapakse,2 Sumadhya Deepika Fernando3 1Department of Pathology, School of Medical Sciences, UNSW, Sydney, NSW, Australia; 2Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka ...
Rodrigo C, Rajapakse S, Fernando SD
doaj
Polymorphic drug metabolising enzymes:Assessment of activities by phenotyping and genotyping in clinical pharmacology [PDF]
Drug effects (pharmacodynamics) are determined by drug concentration at target site and the affinity of the drug for a target. Pharmacogenetics describes inherited differences in drug metabolising enzyme activities and differences in drug transporters ...
Tamminga, Willem Jan
core +2 more sources

