Results 81 to 90 of about 7,683 (208)

Malaria and the traveller [PDF]

, 2005
Malaria has reached epidemic proportions. About 40% of the world’s population live in malarious areas. It is estimated that 400 million people are infected by malaria each year and of these, 1-3 million die, mostly children under five years of age.
Tonna, Antonella, Tonna, Ivan
core  

Adverse effects of the antimalaria drug, mefloquine: due to primary liver damage with secondary thyroid involvement? [PDF]

, 2002
Background Mefloquine is a clinically important antimalaria drug, which is often not well tolerated. We critically reviewed 516 published case reports of mefloquine adverse effects, to clarify the phenomenology of the harms associated with mefloquine ...
Ashley M Croft, Andrew Herxheimer, WD Tigertt, F Nosten, AM Rønn, World Health Organisation, D Overbosch, L Bem, World Health Organisation, P Schlagenhauf, T Weinke, PJ Barrett, D Huzly, MA Phillips, P Schlagenhauf, JC Handschin, MM van Riemsdijk, C Micheo, H Kollaritsch, BA Wolters, FM Smithuis, C Luxemburger, ML Mittelholzer, FO ter Kuile, P Phillips-Howard, B Vanhauwere, NDC Finlayson, CRW Edwards, KN Bangchang, I Gotsman, CAJJ Jaspers, S Takeshima, EC Reisinger, J Neuberger, A Grieco, RC Wittes, EFPM Vuurman, K Meszaros, GM Gullahorn, A Castot, JI Conget, WM Bauer, X Nicolas, LH Schmidt, K Neftel, D Larrey, W Woodtli, G Charmot, J Bernuau, JM Raymond, Y Munera, AM McGregor, JW Barlow, EA Stroev, HR Smith, D Ashby, E Boudreau, E Petersen, VV Olsen, E Ragan, I Potasman, H Folkerts, D Grupp, AM Rønn, M Hollweg, M Heeringa, JB Jensen, IC Bygberg, M Fusetti, JT Lysack, J Van den Ende, DN Durrheim, SS Mangalvedhekar, F Nosten, JC Merritt, P Heno, IC Perry, J Botella de Maglia, HO Lobel   +78 more
core   +2 more sources

Patterns of case management and chemoprevention for malaria-in-pregnancy by public and private sector health providers in Enugu state, Nigeria

BMC Research Notes, 2012
Background Malaria in pregnancy (MIP) is a major disease burden in Nigeria and has adverse consequences on the health of the mother, the foetus and the newborn.
Onwujekwe Ogochukwu C, Soremekun Rebecca O, Uzochukwu Benjamin, Shu Elvis, Onwujekwe Obinna   +4 more
doaj   +1 more source

Safety and Immunogenicity of Live Oral Cholera and Typhoid Vaccines Administered Alone or in Combination with Antimalarial Drugs, Oral Polio Vaccine, or Yellow Fever Vaccine [PDF]

, 2017
The effects of concomitant administration of antimalarial drugs, oral polio vaccine, or yellow fever vaccine on the immune response elicited by the Vibrio cholerae CVD103-HgR and Salmonella typhi Ty21a live oral vaccines were investigated. Healthy adults
Cryz, Stanley J., Herzog, Christian, Kollaritsch, Herwig, Kunz, Christian, Que, John U., Wiedermann, Gerhard   +5 more
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Inactive alleles of cytochrome P450 2C19 may be positively selected in human evolution Genome evolution and evolutionary systems biology [PDF]

, 2014
© 2014 Janha et al.; licensee BioMed Central Ltd.Background: Cytochrome P450 CYP2C19 metabolizes a wide range of pharmacologically active substances and a relatively small number of naturally occurring environmental toxins.
Janha, RE, Linton, KJ, Shaheen, SO, Sisay-Joof, F, Walton, RT, Worwui, A   +5 more
core   +3 more sources

In silico comparative genomics analysis of Plasmodium falciparum for the identification of putative essential genes and therapeutic candidates.

, 2014
A sequence of computational methods was used for predicting novel drug targets against drug resistant malaria parasite Plasmodium falciparum. Comparative genomics, orthologous protein analysis among same and other malaria parasites and protein-protein ...
Altschul, Andrews, Anishetty, Arama, Berman, Bernstein, Bhasin, Boeckmann, Chang, Chawley, Chen, Colovos, Corpet, David Charles Warhurst, Eisenberg, Finn, Franceschini, Ghosh, Irwin, Irwin, Kanehisa, Konc, Krogh, Kushwaha, Larsen, Laskowski, Ludin, Miller, Morris, Mrutyunjay Suar, Mulder, Pieper, Pierleoni, Pontius, Rajani Kanta Mahapatra, Sali, Subhashree Rout, Sun, Tam, von Mering, Wallner, Wiederstein, World Health Organization, Yang, Yeh, Zhexin   +45 more
core   +1 more source

Aktueller Malariaschutz bei Kurzzeitaufenthalt [PDF]

, 2018
Zusammenfassung: In Deutschland werden jährlich ca. 800Malariafälle gemeldet. Für ca.1% der nicht immunen Reisenden endet die Krankheit tödlich.
Hatz, C., Nothdurft, H.
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Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase of isolates from the Amazon Region of Brazil

Memorias do Instituto Oswaldo Cruz, 2000
Since the late 1970s pyrimethamine-sulfadoxine (PS; FansidarTM Hoffman-LaRoche, Basel) has been used as first line therapy for uncomplicated malaria in the Amazon basin.
KF Vasconcelos, CV Plowe, CJ Fontes, D Kyle, DF Wirth, LH Pereira da Silva, MG Zalis   +6 more
doaj   +1 more source

Validation Of Assay Methods For Chlorproguanil And Chlorcycloguanil And Its Application To Pharmacokinetics Studies [PDF]

, 1996
Dua kaedah pengeseian telah dikembangkan dan disahkan bagi analisis klorproguanil dan klorsikloguanil.
Sulaiman, Maryam
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Artenimol–piperaquine in children with uncomplicated imported falciparum malaria: experience from a prospective cohort

Malaria Journal, 2019
Background Although malaria remains one of the major public health threats in inter-tropical areas, there is limited understanding of imported malaria in children by paediatricians and emergency practitioners in non-endemic countries, often resulting in ...
Lauren Pull, Jean-Marc Lupoglazoff, Matthew Beardmore, Jean-François Michel, Pierre Buffet, Olivier Bouchaud, Jean-Yves Siriez   +6 more
doaj   +1 more source