Results 61 to 70 of about 7,683 (208)

Severity of imported malaria: protective effect of taking malaria chemoprophylaxis [PDF]

, 2013
BACKGROUND: Although chemoprophylaxis remains an important strategy for preventing malaria in travellers, its effectiveness may be compromised by lack of adherence. Inappropriate use of chemoprophylaxis is likely to increase the risk of acquiring malaria,
Jaap J van Hellemond, Klaske Vliegenthart-Jongbloed, Mariana de Mendonça Melo, Marlies E van Wolfswinkel, Perry JJ van Genderen, Rob Koelewijn   +5 more
core   +2 more sources

FIGO good practice recommendations on anemia in pregnancy, to reduce the incidence and impact of postpartum hemorrhage (PPH)

International Journal of Gynecology &Obstetrics, Volume 171, Issue 3, Page 993-1007, December 2025.
Abstract Anemia affects 32 million pregnant women globally, contributing annually to more than 115 000 maternal deaths and 591 000 perinatal deaths worldwide. Low‐ and middle‐income countries (LMICs) bear the highest burden of anemia in pregnancy, with nearly 50% of affected pregnant women. It is now 2025, which is WHO's target year for a 50% reduction
Akaninyene E. Ubom, Ferdousi Begum, Diana Ramasauskaite, Albaro J. Nieto‐Calvache, Monica Oguttu, Inês Nunes, Zechariah J. Malel, Jolly Beyeza‐Kashesya, Alison Wright, on behalf of the FIGO Committee on Childbirth and Postpartum Hemorrhage   +9 more
wiley   +1 more source

Ototoxicity of artemether/lumefantrine in the treatment of falciparum malaria: a randomized trial

Malaria Journal, 2008
Background Due to increasing drug resistance, artemisinin-based combination chemotherapy (ACT) has become the first-line treatment of falciparum malaria in many endemic countries. However, irreversible ototoxicity associated with artemether/lumefantrine (
Krause Eike, Girma Tsinuel, Mamo Yoseph, Berens-Riha Nicole, Miranda Isabel, Eshetu Teferi, Gürkov Robert, Schmidt Michael, Hempel John-Martin, Löscher Thomas   +9 more
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

Different mutation patterns of atovaquone resistance to Plasmodium falciparum in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as potential in vivo resistance marker

Malaria Journal, 2003
Background Resistance of Plasmodium falciparum to atovaquone in vitro and in vivo has been associated to mutations in the parasite cytochrome b gene. Methods Cultures were sequentially subjected to increasing doses of atovaquone alone or in combination ...
Salanti Ali, Alifrangis Michael, Schwöbel Babett, Jelinek Tomas   +3 more
doaj   +1 more source

Economics of Malaria Prevention in US Travelers to West Africa [PDF]

, 2013
Background. Pretravel health consultations help international travelers manage travel-related illness risks through education, vaccination, and medication. This study evaluated costs and benefits of that portion of the health consultation associated with
Adachi, Kenji, Arguin, Paul, Brunette, Gary, Coleman, Margaret S, Jentes, Emily S, Khan, Nomana, Knouse, Mark, MD, LaRocque, Regina C, Meltzer, Martin I, Rao, Sowmya R, Ryan, Edward T, Sotir, Mark J   +11 more
core   +1 more source

Antenatal medication management for women with sickle‐cell disease: A systematic review

Pregnancy, Volume 1, Issue 4, July 2025.
Abstract Background Improvements in sickle‐cell disease (SCD) treatment have led to an increasing number of individuals surviving to reproductive age. However, pregnancy in women with SCD carries a heightened risk of maternal and fetal complications.
Yaneve N. Fonge, Kelli D. Barbour, Sarah Boudova, Jen Sothornwit, Chetta Ngamjarus, Porjai Pattanittum, Apiwat Jongjakapun, Termtem Waidee, Nampet Jampathong, Pisake Lumbiganon, Beth L. Pineles   +10 more
wiley   +1 more source

A Novel Inhibitor against the Bromodomain Protein 1 of the Malaria Pathogen Plasmodium Falciparum

ChemMedChem, Volume 20, Issue 11, June 2, 2025.
This article presents the development of a first‐in‐class inhibitor targeting the bromodomain protein PfBDP1 in Plasmodium falciparum, the deadliest variant of the malaria‐causing Plasmodium parasites. Through structure‐based drug design, the inhibitor interactions were characterized via X‐ray crystallography and isothermal titration calorimetry ...
Marius Amann, Robin Warstat, Kay Kristin Rechten, Philip Theuer, Magdalena Schustereder, Sophie Clavey, Bernhard Breit, Oliver Einsle, Martin Hügle, Michaela Petter, Stefan Günther   +10 more
wiley   +1 more source

A survey on outcomes of accidental atovaquone–proguanil exposure in pregnancy

Malaria Journal, 2018
Background Malaria chemoprophylaxis options in pregnancy are limited, and atovaquone–proguanil (AP) is not recommended because of insufficient safety evidence.
Kathrine R. Tan, Jessica K. Fairley, Mengxi Wang, Julie R. Gutman   +3 more
doaj   +1 more source

In vitro activity of antimalarials against clinical isolates of Plasmodium falciparum in Yaounde, Cameroon [PDF]

, 1996
The in vitro activity of nine antimalarials was determined against 119 fresh clinical isolates of #Plasmodium falciparum$ obtained from symptomatic indigenous patients in Yaounde, Cameroun, using the isotopic semimicrotest.
Basco, L., Bickii, J., Ringwald, Pascal
core   +1 more source