Results 51 to 60 of about 3,493 (156)

Confirmation of emergence of mutations associated with atovaquone-proguanil resistance in unexposed Plasmodium falciparum isolates from Africa

Malaria Journal, 2006
Background In vitro and in vivo resistance of Plasmodium falciparum to atovaquone or atovaquone-proguanil hydrochloride combination has been associated to two point mutations in the parasite cytochrome b (cytb) gene (Tyr268Ser and Tyr268Asn).
Kyle Dennis E, Sowunmi Akintunde, Sarr Ousmane, Milner Danny, Folarin Onikepe A, Gbotosho Grace O, Happi Christian T, Milhous Wilbur K, Wirth Dyann F, Oduola Ayoade MJ   +9 more
doaj   +1 more source

"Pyrimethamine and Proguanil Resistance-Conferring Key Mutations in Dihydrofolate Reductase Gene of Plasmodium falciparum Isolates from Iran" [PDF]

Iranian Journal of Public Health, 2003
Using mutation specific PCR assay and analysis of position 108 amino acid in dihydrofolate reductase-thymidilate synthase gene in 70 Plasmodium falciparum isolates of malarial patients from southern areas of Iran, showed 4 different situations: iwild ...
AA Eskandarian, H Keshavarz, F Mahboudi
doaj   +2 more sources

Patterns of case management and chemoprevention for malaria-in-pregnancy by public and private sector health providers in Enugu state, Nigeria

BMC Research Notes, 2012
Background Malaria in pregnancy (MIP) is a major disease burden in Nigeria and has adverse consequences on the health of the mother, the foetus and the newborn.
Onwujekwe Ogochukwu C, Soremekun Rebecca O, Uzochukwu Benjamin, Shu Elvis, Onwujekwe Obinna   +4 more
doaj   +1 more source

Atovaquone-Proguanil: A Promising Therapy for Persistent Relapsing Babesiosis

Case Reports in Infectious Diseases
We report a challenging case of persistent relapsing babesiosis in an immunocompromised host that was successfully managed with atovaquone-proguanil (Malarone).
Mahum Shahid, Brendan Wechsler, Vinod Parameswaran, Mark Anthony Diaz   +3 more
doaj   +1 more source

Artenimol–piperaquine in children with uncomplicated imported falciparum malaria: experience from a prospective cohort

Malaria Journal, 2019
Background Although malaria remains one of the major public health threats in inter-tropical areas, there is limited understanding of imported malaria in children by paediatricians and emergency practitioners in non-endemic countries, often resulting in ...
Lauren Pull, Jean-Marc Lupoglazoff, Matthew Beardmore, Jean-François Michel, Pierre Buffet, Olivier Bouchaud, Jean-Yves Siriez   +6 more
doaj   +1 more source

Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase of isolates from the Amazon Region of Brazil

Memorias do Instituto Oswaldo Cruz, 2000
Since the late 1970s pyrimethamine-sulfadoxine (PS; FansidarTM Hoffman-LaRoche, Basel) has been used as first line therapy for uncomplicated malaria in the Amazon basin.
KF Vasconcelos, CV Plowe, CJ Fontes, D Kyle, DF Wirth, LH Pereira da Silva, MG Zalis   +6 more
doaj   +1 more source

Therapy of uncomplicated falciparum malaria in Europe: MALTHER – a prospective observational multicentre study

Malaria Journal, 2012
Background Malaria continues to be amongst the most frequent infectious diseases imported to Europe. Whilst European treatment guidelines are based on data from studies carried out in endemic areas, there is a paucity of original prospective treatment ...
Bouchaud Olivier, Mühlberger Nikolai, Parola Philippe, Calleri Guido, Matteelli Alberto, Peyerl-Hoffmann Gabriele, Méchaï Frédéric, Gautret Philippe, Clerinx Jan, Kremsner Peter G, Jelinek Tomas, Kaiser Annette, Beltrame Anna, Schmid Matthias L, Kern Peter, Probst Meike, Bartoloni Alessandro, Weinke Thomas, Grobusch Martin P   +18 more
doaj   +1 more source

Artemisinin Combination Therapy Can Result in Clinical Failure If Oral Therapy Is Not Directly Observed

Canadian Journal of Infectious Diseases and Medical Microbiology, 2013
Intravenous artesunate therapy is the first-line therapy for severe malaria, and is highly efficacious when used in combination with an oral partner drug such as doxycycline or atovaquone-proguanil.
Wilson W Chan, Divya Virmani, Dylan R Pillai   +2 more
doaj   +1 more source

Compliance with Primary Malaria Chemoprophylaxis: Is Weekly Prophylaxis Better Than Daily Prophylaxis?

Patient Preference and Adherence, 2020
Chaturaka Rodrigo,1 Senaka Rajapakse,2 Sumadhya Deepika Fernando3 1Department of Pathology, School of Medical Sciences, UNSW, Sydney, NSW, Australia; 2Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka ...
Rodrigo C, Rajapakse S, Fernando SD
doaj  

Tolerancia y reacciones adversas en la quimioprofilaxis antipalúdica de larga duración: una revisión bibliográfica

ENE. Revista de Enfermería
Las Fuerzas Armadas españolas están desplegadas en diferentes áreas donde la transmisión de malaria se produce de forma importante. Los relevos de personal varían entre 4 y 6 meses, periodos en los que las tropas han de mantener una quimioprofilaxis ...
Carlos Fuentes Mora
doaj   +1 more source