Results 121 to 130 of about 11,901 (220)
Methionine adenosyltransferases in liver cancer. [PDF]
, 2019 Methionine adenosyltransferases (MATs) are essential enzymes for life as they produce S-adenosylmethionine (SAMe), the biological methyl donor required for a plethora of reactions within the cell.
Barbier-Torres, Lucia +4 more
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Cytochrome c: Surfing Off of the Mitochondrial Membrane on the Tops of Complexes III and IV [PDF]
, 2019 The proper arrangement of protein components within the respiratory electron transport chain is nowadays a matter of intense debate, since altering it leads to cell aging and other related pathologies.
Díaz Moreno, Irene +4 more
core +1 more source
Prohibitin modulates periodontium differentiation in mice development
Frontiers in Cell and Developmental BiologyIntroduction: Prohibitin (PHB) is an essential scaffold protein that modulates signaling pathways controlling cell survival, metabolism, inflammation, and bone formation. However, its specific role in periodontium development remains less understood. This study aims to elucidate the expression pattern and function of PHB in periodontium development and
Yam Prasad Aryal +17 more
openaire +3 more sources
Inhibition of insulin/IGF‐1 receptor signaling protects from mitochondria‐mediated kidney failure
EMBO Molecular Medicine, 2015 Mitochondrial dysfunction and alterations in energy metabolism have been implicated in a variety of human diseases. Mitochondrial fusion is essential for maintenance of mitochondrial function and requires the prohibitin ring complex subunit prohibitin‐2 (
Christina Ising +19 more
doaj +1 more source
Gender-specific changes in energy metabolism and protein degradation as major pathways affected in livers of mice treated with ibuprofen. [PDF]
, 2020 Ibuprofen, an inhibitor of prostanoid biosynthesis, is a common pharmacological agent used for the management of pain, inflammation and fever. However, the chronic use of ibuprofen at high doses is associated with increased risk for cardiovascular, renal,
Gomes, Aldrin V +5 more
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PLoS ONEProhibitin 1 (PHB1) and prohibitin 2 (PHB2) are highly conserved proteins belonging to the stomatin-prohibitin flotillin-HflC/K (SPFH) protein superfamily. They are ubiquitously expressed and implicated in the regulation of cell proliferation, migration,
Mei Li +9 more
doaj +1 more source
Functional proteomics of nonalcoholic steatohepatitis: mitochondrial proteins as targets of S-adenosylmethionine [PDF]
, 2003 Recent work shows that S-adenosylmethionine (AdoMet) helps maintain normal liver function as chronic hepatic deficiency results in spontaneous development of steatohepatitis and hepatocellular carcinoma.
Avila, M.A. (Matías Antonio) +7 more
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Viral hijacking of cellular metabolism. [PDF]
, 2019 This review discusses the current state of the viral metabolism field and gaps in knowledge that will be important for future studies to investigate.
Ch'ng, James +2 more
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Fatty acids do not activate UCP2 in pancreatic beta cells: comparison with UCP1 [PDF]
, 2018 UCP2 is expressed in pancreatic β cells where its postulated uncoupling activity will modulate glucose-induced changes in ATP/ADP ratio and insulin secretion. The consequences of UCP2 over/underexpression on β-cell function has mainly been studied in the
Assimacopoulos-Jeannet, Françoise +5 more
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