Results 51 to 60 of about 46,567 (296)

Hard and soft governance mechanisms for large projects. A historical perspective

Journal of Management History
Purpose Drawing motivation from the greater exposure to uncertainty and condition changes that affect large projects due to their long lifecycle, this paper aims to investigate how the time factor affects the use of governance mechanisms to pursue the success of these projects.
GIORGINO MARIA CLEOFE, BARNABE' FEDERICO
openaire   +3 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Independent accountability mechanisms: Promotion of standards, good governance and accountability

Since 1993, international accountability mechanisms (IAMs) have been established by international financial institutions (IFIs) including the World Bank and regional development banks to handle problem projects which adversely impact on people.
Nanwani, Suresh, McIntyre, Owen
core   +1 more source

Corporate Governance and firm value: evidence from Colombia and Mexico [PDF]

, 2014
This research is the result of the author’s quest to answer the question whether Corporate Governance is effective in Emerging Markets. Literature on Corporate Governance in the emerging markets of Latin America is limited mostly due to the relatively
Davila, Juan Pablo
core  

Development of a data-driven urban immunity assessment model: providing a new benchmark for urban governance under public health emergencies

Frontiers in Public Health
Public health emergencies (PHEs) pose significant challenges to global urban governance systems, necessitating the establishment of more efficient and dynamically adaptive response mechanisms.
Peng Cui, Peng Cui, Saiya Cao, Ruize Qin, Fan Zhang   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The Governance of PPP Project Resilience: A Hybrid DMATEL-ISM Approach

Systems
Considering the inherent characteristics of long-term agreements, public–private partnership (PPP) projects are confronted with diverse uncertainties and external challenges.
Zhankun Liu, Nannan Wang, Qiushi Du
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Building project competence : developing dynamic capabilities with knowledge governance mechanisms

, 2013
This research investigates the development of project competence, and particularly, three related dynamic capabilities (shifting, adapting, leveraging) that contribute to project competence development. In doing so, we make use of the emerging literature
Wiewiora, Anna, Söderlund, Jonas, Pemsel, Sofia   +2 more
core