Results 81 to 90 of about 520,390 (301)

Railway scheduling reduces the expected project makespan. [PDF]

The Critical Chain Scheduling and Buffer Management (CC/BM) methodology, proposed by Goldratt (1997), introduced the concepts of feeding buffers, project buffers and resource buffers as well as the roadrunner mentality.
Demeulemeester, Erik, Tian, Wendi
core  

Proactive project scheduling in an R&D department: a bi-objective genetic algorithm [PDF]

, 2015
In this paper, we present part of a study on stochastic, dynamic project scheduling in an R&D Department of a leading home appliances company in Turkey.
Capa, Canan, Ulusoy, Gunduz, Ulusoy, Gündüz, Çapa, Canan   +3 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Software Project Scheduling Problem: A Review

مهندسی مخابرات جنوب
The software project scheduling problem (SPSP) is one of the most important activities in software project development. One of the main reasons for unsuccessful software project completion is non-compliance with cost and schedule plans, often due to ...
Javad Pashaei Barbin, Mahdi Jalali
doaj  

Project scheduling under undertainty – survey and research potentials. [PDF]

The vast majority of the research efforts in project scheduling assume complete information about the scheduling problem to be solved and a static deterministic environment within which the pre-computed baseline schedule will be executed. However, in the
Herroelen, Willy, Leus, Roel
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Multi-Project Scheduling with Uncertainty and Resource Flexibility: A Narrative Review and Exploration of Future Landscapes

Algorithms
This paper presents a narrative review on the Resource-Constrained Multi-Project Scheduling Problem (RCMPSP) under uncertainty and resource flexibility.
Marzieh Aghileh, Anabela Tereso, Filipe Alvelos, Maria Odete Monteiro Lopes   +3 more
doaj   +1 more source

Using Fuzzy Clustering Chaotic-based Differential Evolution to solve multiple resources leveling in the multiple projects scheduling prob

Alexandria Engineering Journal, 2016
Project scheduling is an important part of construction project planning. Resource leveling is the process used within project scheduling to reduce fluctuations in resource usage over the period of project implementation.
Duc-Hoc Tran, Min-Yuan Cheng, Anh-Duc Pham   +2 more
doaj   +1 more source

An overview of recent research results and future research avenues using simulation studies in project management [PDF]

, 2013
This paper gives an overview of three simulation studies in dynamic project scheduling integrating baseline scheduling with risk analysis and project control. This integration is known in the literature as dynamic scheduling.
Vanhoucke, Mario
core   +4 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source