Results 61 to 70 of about 12,336,647 (296)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
IEEE AccessThis paper presents a new three-term hybrid conjugate gradient projection method for handling large-scale convex-constrained nonlinear monotone equations that are prevalent in fields such as engineering optimization, data science, and signal processing ...
Xiaowei Fang, Yufan Rao, Jingchi Wang
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Interactive data exploration with targeted projection pursuit [PDF]
, 2009 Data exploration is a vital, but little considered, part of the scientific process; but few visualisation tools can cope with truly complex data. Targeted Projection Pursuit (TPP) is an interactive data exploration technique that provides an intuitive ...
Faith, Joe
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Updates on adaptive orientation of projection planes method
, 2018 The proposed method: adaptive orientation of projection planes is experimenting an adaptive orientation method to find a better oriented plane for projection.
Zaharia, Titus, Cao, Chao, Preda, Marius
core +6 more sources
Numerical analysis of low-Reynolds-number flow past an array of pillars with surface slip
Nihon Kikai Gakkai ronbunshuIn the development of micro- and nano-fluidic devices incorporating nanopillar structures to create nanoscale confined flow paths, it is important to consider the slip velocity on the pillar surface, which reflects the local wettability.
Takehiro FUJII, Takeshi OMORI
doaj +1 more source
Projection Pursuit for Exploratory Supervised Classification [PDF]
In high-dimensional data, one often seeks a few interesting low-dimensional projections that reveal important features of the data. Projection pursuit is a procedure for searching high-dimensional data for interesting low-dimensional projections via the ...
Thomas Lumley +3 more
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FRINGE PROJECTION METHOD FOR TOPOGRAPHY AND DYNAMIC DEFORMATION MEASUREMENT [PDF]
, 2008 "The thesis deals with the application of the fringe projection method for topography and dynamic deformation measurement. In the first part, we present an analysis of the influence of the grating period used in fringe projection technique for topography
ANDREA LEON HUERTA
core
Solution of Large Stochastic Finite Element Problems – Application to ECT-NDT [PDF]
, 2013 Version éditeur disponible à cette adresse : http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6514633This paper describes an efficient bloc iterative solver for the Spectral Stochastic Finite Element Method (SSFEM). The SSFEM was widely used to
MOREAU, Olivier +3 more
core +1 more source