Results 81 to 90 of about 11,611,558 (295)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Second-order fully discretized projection method for incompressible Navier-Stokes equations

open access: yesElectronic Journal of Differential Equations, 2016
A second-order fully discretized projection method for the incompressible Navier-Stokes equations is proposed. It is an explicit method for updating the pressure field. No extra conditions of immediate velocity fields are needed.
Daniel X. Guo
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Projection-pursuit-based method for blind separation of nonnegative sources

open access: yes, 2013
This paper presents a projection pursuit (PP) based method for blind separation of nonnegative sources. First, the available observation matrix is mapped to construct a new mixing model, in which the inaccessible source matrix is normalized to be column ...
Y Rong (13483264)   +3 more
core  

A Convex Variational Interactive Model with Projection Method for Digital Images Partitioning

open access: yesJournal of ICT
Digital image partitioning separates the foreground of an image from the background for subsequent analysis. In literature, the variational global model is frequently employed for digital images partitioning; however, it has been shown to underperform ...
Abdul Kadir Jumaat   +2 more
doaj   +1 more source

Projection solutions of Frobenius-Perron operator equations

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1993
We construct in this paper the first order and second order piecewise polynomial finite approximation schemes for the computation of invariant measures of a class of nonsingular measurable transformations on the unit interval of the real axis.
Jiu Ding, Tien Tien Li
doaj   +1 more source

On the O ( 1 / t ) $O(1/t)$ convergence rate of the alternating direction method with LQP regularization for solving structured variational inequality problems

open access: yesJournal of Inequalities and Applications, 2016
In this paper, we propose a parallel descent LQP alternating direction method for solving structured variational inequality with three separable operators. The O ( 1 / t ) $O(1/t)$ convergence rate for this method is studied.
Abdellah Bnouhachem   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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