Results 71 to 80 of about 11,611,558 (295)

Projection Pursuit for Exploratory Supervised Classification [PDF]

open access: yes
In high-dimensional data, one often seeks a few interesting low-dimensional projections that reveal important features of the data. Projection pursuit is a procedure for searching high-dimensional data for interesting low-dimensional projections via the ...
Thomas Lumley   +3 more
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Numerical analysis of low-Reynolds-number flow past an array of pillars with surface slip

open access: yesNihon Kikai Gakkai ronbunshu
In the development of micro- and nano-fluidic devices incorporating nanopillar structures to create nanoscale confined flow paths, it is important to consider the slip velocity on the pillar surface, which reflects the local wettability.
Takehiro FUJII, Takeshi OMORI
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Approximations of solutions for a class of conditionally well-posed integro-differential equations

open access: yesУчёные записки Казанского университета: Серия Физико-математические науки
In this article, for a specific class of conditionally well-posed integro-differential equations in a novel pair of weighted Sobolev spaces, an alternative method for constructing approximations (particularly finite-dimensional ones) to the solution of ...
J. R. Agachev, M. Yu. Pershagin
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Teaching medical students hematopathology: a randomized crossover study comparing direct inspection by light microscope versus projected images

open access: yesFrontiers in Medicine
BackgroundStudents’ ability to diagnose various blood disorders could be substantially improved by continuously reviewing approaches toward teaching hematology.
Sultan Alqahtani   +6 more
doaj   +1 more source

A Projection Model of Neutrosophic Numbers for Multiple Attribute Decision Making of Clay-Brick Selection [PDF]

open access: yesNeutrosophic Sets and Systems, 2016
Brick plays a significant role in building construction. So we should use the effective mathematical decision making tool to select quality clay-bricks for building construction.
Jiqian Chen, Jun Ye
doaj  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

The Similarity Measures for Linguistic q-Rung Orthopair Fuzzy Multi-Criteria Group Decision Making Using Projection Method

open access: yesIEEE Access, 2019
The linguistic q-rung orthopair fuzzy sets (Lq-ROFSs) can fully represent linguistic evaluation information by adjusting the parameter $q$ to describe the range of uncertain information.
Dan Peng   +3 more
doaj   +1 more source

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