Results 71 to 80 of about 12,336,647 (296)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Approximations of solutions for a class of conditionally well-posed integro-differential equations
Учёные записки Казанского университета: Серия Физико-математические наукиIn this article, for a specific class of conditionally well-posed integro-differential equations in a novel pair of weighted Sobolev spaces, an alternative method for constructing approximations (particularly finite-dimensional ones) to the solution of ...
J. R. Agachev, M. Yu. Pershagin
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Visual Instruction and the Projection Method
, 1927 VISUAL INSTRUCTION AND THE PROJECTION METHOD Visual Instruction and the Projection Method (6 ...
Jacobj, Carl
core +1 more source
Frontiers in MedicineBackgroundStudents’ ability to diagnose various blood disorders could be substantially improved by continuously reviewing approaches toward teaching hematology.
Sultan Alqahtani +6 more
doaj +1 more source
A Projection Model of Neutrosophic Numbers for Multiple Attribute Decision Making of Clay-Brick Selection [PDF]
Neutrosophic Sets and Systems, 2016 Brick plays a significant role in building construction. So we should use the effective mathematical decision making tool to select quality clay-bricks for building construction.
Jiqian Chen, Jun Ye
doaj
Projection-pursuit-based method for blind separation of nonnegative sources
, 2013 This paper presents a projection pursuit (PP) based method for blind separation of nonnegative sources. First, the available observation matrix is mapped to construct a new mixing model, in which the inaccessible source matrix is normalized to be column ...
Y Rong (13483264) +3 more
core
Efficient Algorithms for Solution of the Adjoint Compressible Navier-Stokes Equations with Applications [PDF]
, 2006 The complete discrete adjoint equations for an unstructured finite volume compressible Navier-Stokes solver are discussed with respect to the memory and time efficient evaluation of their residuals, and their solution.
Brezillon, Joel +2 more
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source