Results 71 to 80 of about 1,399,718 (337)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Geometric and projection effects in Kramers-Moyal analysis
, 2009 Kramers-Moyal coefficients provide a simple and easily visualized method with which to analyze stochastic time series, particularly nonlinear ones. One mechanism that can affect the estimation of the coefficients is geometric projection effects. For some
H. Kantz +3 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Constructing Fewer Open Cells by GCD Computation in CAD Projection
, 2014 A new projection operator based on cylindrical algebraic decomposition (CAD) is proposed. The new operator computes the intersection of projection factor sets produced by different CAD projection orders.
Dai, Liyun, Han, Jingjun, Xia, Bican
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Surface Projection Method for Visualizing Volumetric Data [PDF]
, 2006 The goal of this project was to explore, develop, and implement additional visualization methods for volumetric data within MindSeer. This paper discusses the implementation of one such visualization method, the surface projection method, and compares it
Lincoln, Peter
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Perfect Perspective: A Mathematical Analysis of Perspective Using Tools Available to Middle School Students [PDF]
, 2003 This paper examines the basic properties of perspective drawings, the history of perspective drawings, and the basic mathematics of perspective. Using a side view and a top view of a three-dimensional projection, similar triangles can be used to find ...
Griffin, W.
core +1 more source
Comparative Analysis of Wavelet Bases for Solving First-Kind Fredholm Integral Equations
ComputationThis research presents a comparative analysis of numerical methods for solving first-kind Fredholm integral equations using the Bubnov–Galerkin method with various wavelet and orthogonal polynomial bases.
Nurlan Temirbekov +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source