Results 71 to 80 of about 1,750 (261)

Discrete gauge groups in F-theory models on genus-one fibered Calabi-Yau 4-folds without section

open access: yesJournal of High Energy Physics, 2017
We determine the discrete gauge symmetries that arise in F-theory compactifications on examples of genus-one fibered Calabi-Yau 4-folds without a section.
Yusuke Kimura
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Projective Metrizability and Formal Integrability

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2011
The projective metrizability problem can be formulated as follows: under what conditions the geodesics of a given spray coincide with the geodesics of some Finsler space, as oriented curves.
Ioan Bucataru, Zoltán Muzsnay
doaj   +1 more source

Some designs and codes from L_2(q) [PDF]

open access: yesTransactions on Combinatorics, 2014
For $q \in \{7,8,9,11,13,16\}$, we consider the primitive actions of $L_2(q)$ and use Key-Moori Method 1 as described in [Codes, designs and graphs from the Janko groups {$J_1$} and {$J_2$}, {\em J. Combin. Math. Combin.
Jamshid Moori   +1 more
doaj  

Heterotic instanton superpotentials from complete intersection Calabi-Yau manifolds

open access: yesJournal of High Energy Physics, 2017
We study Pfaffians that appear in non-perturbative superpotential terms arising from worldsheet instantons in heterotic theories. A result by Beasley and Witten shows that these instanton contributions cancel among curves within a given homology class ...
Evgeny Buchbinder   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

On a generalization of I-regularity

open access: yesOpen Mathematics
Let SS be a pomonoid. The projectivity and strong flatness of right SS-posets have been central topics in the homological classification of pomonoids in recent decades. In 2005, Shi et al. introduced II-regular SS-posets and proved that all its cyclic SS-
Qiao Husheng, Feng Leting
doaj   +1 more source

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