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Microorganisms, 2021 Corynebacterium glutamicum is a prominent production host for various value-added compounds in white biotechnology. Gene repression by dCas9/clustered regularly interspaced short palindromic repeats (CRISPR) interference (CRISPRi) allows for the ...
Vanessa L. Göttl +5 more
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Marine Drugs, 2023 The marine carotenoid astaxanthin is one of the strongest natural antioxidants and therefore is used in a broad range of applications such as cosmetics or nutraceuticals.
Jan Seeger +2 more
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Improved Plasmid-Based Inducible and Constitutive Gene Expression in Corynebacterium glutamicum
Microorganisms, 2021 Corynebacterium glutamicum has been safely used in white biotechnology for the last 60 years and the portfolio of new pathways and products is increasing rapidly.
Nadja A. Henke +2 more
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Molecules, 2023 Circular economy holds great potential to minimize the use of finite resources, and reduce waste formation by the creation of closed-loop systems. This also pertains to the utilization of sidestreams in large-scale biotechnological processes.
Ina Schmitt +5 more
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Prediction of Metabolic Pathways Involvement in Prokaryotic UniProtKB Data by Association Rule Mining [PDF]
, 2016 The widening gap between known proteins and their functions has encouraged the development of methods to automatically infer annotations. Automatic functional annotation of proteins is expected to meet the conflicting requirements of maximizing ...
Boudellioua, Imane +4 more
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BMC Microbiology, 2020 Background The Gram-positive facultative methylotrophic bacterium Bacillus methanolicus uses the sedoheptulose-1,7-bisphosphatase (SBPase) variant of the ribulose monophosphate (RuMP) cycle for growth on the C1 carbon source methanol.
Johannes Pfeifenschneider +4 more
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Fermentation, 2023 Corynebacterium glutamicum is prominent in the industrial production of secreted amino acids. Notably, it naturally accumulates the carotenoid pigment decaprenoxanthin in its membranes. Metabolic engineering enabled the production of astaxanthin. Here, a
Florian Meyer +4 more
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Frontiers in Bioengineering and Biotechnology, 2021 L-Carnitine is a bioactive compound derived from L-lysine and S-adenosyl-L-methionine, which is closely associated with the transport of long-chain fatty acids in the intermediary metabolism of eukaryotes and sought after in the pharmaceutical, food, and
Pierre Kugler +3 more
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A Study on the Origin of Peroxisomes: Possibility of Actinobacteria Symbiosis [PDF]
, 2008 The origin of peroxisomes as having developed from the endoplasmic reticulum (ER) was proposed on the basis of the similarity between some peroxisomal proteins and ER proteins, and the localization of some peroxisomal proteins on the ER.
Duhita Narendra +5 more
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Microorganisms, 2021 N-alkylated amino acids occur widely in nature and can also be found in bioactive secondary metabolites such as the glycopeptide antibiotic vancomycin and the immunosuppressant cyclosporine A.
Anastasia Kerbs +3 more
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