Results 81 to 90 of about 171,661 (301)

Supercritical carbon dioxide extraction of astaxanthin from Corynebacterium glutamicum

Bioresources and Bioprocessing
Astaxanthin, a red carotenoid with potent antioxidant properties, holds significant value in the feed, cosmetics, and nutraceutical industries. While traditionally sourced from microalgae, Corynebacterium glutamicum, a well-established industrial ...
Jan Seeger, Maximilian Zäh, Volker F. Wendisch, Christoph Brandenbusch, Nadja A. Henke   +4 more
doaj   +1 more source

The prokaryotic selenoproteome [PDF]

EMBO reports, 2004
In the genetic code, the UGA codon has a dual function as it encodes selenocysteine (Sec) and serves as a stop signal. However, only the translation terminator function is used in gene annotation programs, resulting in misannotation of selenoprotein genes. Here, we applied two independent bioinformatics approaches to characterize a selenoprotein set in
Kryukov, Gregory V., Gladyshev, Vadim N.
openaire   +2 more sources

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Two routes for tyrosol production by metabolic engineering of Corynebacterium glutamicum

Biotechnology for Biofuels and Bioproducts
Background The phenolic compound tyrosol is widely used in the pharmaceutical industry, owing to its beneficial effects on human health and its use as a precursor for key pharmaceuticals, including β1-receptor blockers. Tyrosol can be found in olive oil,
Nora Junker, Sara-Sophie Poethe, Volker F. Wendisch   +2 more
doaj   +1 more source

Structural divergence of paralogous S components from ECF-type ABC transporters [PDF]

, 2012
Energy coupling factor (ECF) proteins are ATP-binding cassette transporters involved in the import of micronutrients in prokaryotes. They consist of two nucleotide-binding subunits and the integral membrane subunit EcfT, which together form the ECF ...
Beek, Josy ter,, Berntsson, Ronnie P.-A.,, Duurkens, Ria H.,, Majsnerowska, Maria,, Poolman, Bert,, Puri, Pranav,, Slotboom, Dirk-Jan,   +6 more
core   +4 more sources

Miniature Robotic Swimmer with Precise 2D Motion Control via Acoustic Vortex‐Induced Propulsion

Advanced Science, EarlyView.
In this work, a miniature robotic swimmer achieves precise 2D motion using sound waves with customized 3D‐printed lenses. Localized acoustic vortices drive both translation and rotation of the swimmer without mechanical parts. This contactless approach offers a novel route to controlled micro‐scale movement, with promising applications in biomedical ...
Chadi Ellouzi, Nicholas Andrianto, Glen Vosgerichian, Farhood Aghdasi, Joshua Lloyd, Ali Zabihi, Chen Shen   +6 more
wiley   +1 more source

Fermentative Production of N-Alkylated Glycine Derivatives by Recombinant Corynebacterium glutamicum Using a Mutant of Imine Reductase DpkA From Pseudomonas putida

Frontiers in Bioengineering and Biotechnology, 2019
Sarcosine, an N-methylated amino acid, shows potential as antipsychotic, and serves as building block for peptide-based drugs, and acts as detergent when acetylated.
Melanie Mindt, Silvin Hannibal, Maria Heuser, Joe Max Risse, Keerthi Sasikumar, K. Madhavan Nampoothiri, Volker F. Wendisch   +6 more
doaj   +1 more source

Enhancement of the stability of genetic switches by overlapping upstream regulatory domains [PDF]

, 2003
We study genetic switches formed from pairs of mutually repressing operons. The switch stability is characterised by a well defined lifetime which grows sub-exponentially with the number of copies of the most-expressed transcription factor, in the regime
A. Arkin, D. T. Gillespie, M. Ptashne, R. Wagner, T. B. Kepler, W. Bialek, Z. Szallasi   +6 more
core   +1 more source

Natural Negative Feedback Loops Confer Indica‐Japonica Differentiation for Grain Size Homeostasis in Rice

Advanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li, Meng‐en Wu, Ziqi Qiao, Junkui Huang, Juncheng Zhang, Yang Ding, Junqing Zhu, Jingyue Xu, Yuxin Huang, Wei Li, Xiaomin Su, Yue Ding, Jianwei Zhang, Yibo Li   +13 more
wiley   +1 more source

Improved Astaxanthin Production with Corynebacterium glutamicum by Application of a Membrane Fusion Protein

Marine Drugs, 2019
Astaxanthin is one of the strongest natural antioxidants and a red pigment occurring in nature. This C40 carotenoid is used in a broad range of applications such as a colorant in the feed industry, an antioxidant in cosmetics or as a supplement in human ...
Nadja A. Henke, Volker F. Wendisch
doaj   +1 more source