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Recent Advances in Gastrointestinal Prokinetic Agents
2006Publisher Summary This chapter discusses various gastrointestinal prokinetic agents, such as dopamine D 2 receptor antagonists, serotonin 5-hydroxytryptamine (5-HT 4 ) receptor agonists, serotonin 5-HT 3 receptor agonists, cholecystokinin CCK a receptor antagonists, motilin receptor agonists, and μ -opioid receptor antagonists.
David A. Sandham +1 more
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Developments and Advances in Gastrointestinal Prokinetic Agents
2011Publisher Summary This chapter highlights the advances made in the area of gastrointestinal (GI) prokinetics in both the clinical and early discovery phases between 2006 and 2010, with an emphasis on the more recent developments. The quality of life for people suffering from functional gastrointestinal disorders (FGIDs) is significantly reduced when ...
James W. Dale +2 more
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The effects of renzapride, a novel prokinetic agent, in diabetic gastroparesis
Alimentary Pharmacology & Therapeutics, 1991SUMMARYGastric emptying was measured in 9 diabetic patients with autonomic neuropathy (Group 1) and 8 normal controls (Group 2) on 4 occasions after swallowing placebo, 0.5, 1.0 or 2.0 mg of the newly developed prokinetic drug renzapride given double‐blind and in random order.
A D, Mackie +5 more
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Efficacy of Prokinetic Agents in Improving Bowel Preparation for Colonoscopy
Digestion, 2008<i>Background and Aim: </i>Colonoscopy plays an important role in the diagnosis and treatment of gastrointestinal illness in both Western countries and Japan. However, preparative bowel cleansing for colonoscopy is frequently troublesome for elderly and/or constipated patients, since they must drink larger volumes of lavage solution for ...
Yuko, Mishima +9 more
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Recent developments in gastrointestinal prokinetic agents
Expert Opinion on Therapeutic Patents, 2008Background: Prokinetic agents are employed to reverse impaired gastrointestinal motility arising from functional disorders such as constipation-dependent irritable bowel syndrome and functional dyspepsia, as well as chronic constipation and gastro-oesophageal reflux disease.
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[Prokinetic agents--their contribution to practice of gastroenterology].
Vnitrni lekarstvi, 2011Motility plays a fundamental role in the functioning of the gastrointestinal tract. Prokinetic agents are thus an important treatment modality in patients with functional and certain organ diseases with underlying functional modifications. Gastro-oesophageal reflux disease is frequently associated with a disorder ofoesophageal motility, an alteration ...
A, Hep, J, Dolina
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Use of Prokinetic Agents in Hospitalised Adult Patients: A Scoping Review
Acta Anaesthesiologica Scandinavica, 2023Waleed Alhazzani +2 more
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