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Prolactin and Autoimmunity [PDF]

open access: yesFrontiers in Immunology, 2018
The great asymmetry of autoimmune diseases between genders represents one of the most enigmatic observations among the mosaic of autoimmunity. Sex hormones are believed to play a crucial role on this dimorphism.
V. Borba   +2 more
semanticscholar   +5 more sources

Confusion in the interpretation of prolactin levels caused by inappropriately low reference intervals [PDF]

open access: yesEndocrine Connections
Objective: Serum prolactin measurements are important in the differential diagnosis of pituitary masses and subfertility. We observed discrepancies in serum prolactin levels in several patients measured with different immunoassays. Despite differences in
Yanaika S Sabogal Piñeros   +4 more
doaj   +2 more sources

Prolactin protects hippocampal neurons against H2O2-induced neurotoxicity by suppressing BAX and NOX4 via the NF-κB signaling pathway. [PDF]

open access: yesPLoS ONE
Reactive oxygen species (ROS) are physiological byproducts of neuronal metabolism. However, an imbalance between ROS generation and antioxidant capacity, often driven by dysregulated pro-oxidant enzymes like nicotinamide adenine dinucleotide phosphate ...
Fernando Macías   +4 more
doaj   +2 more sources

Prolactin at moderately increased levels confers a neuroprotective effect in non-secreting pituitary macroadenomas.

open access: yesPLoS ONE, 2022
ContextProlactin, a hormone synthesized by the anterior pituitary gland demonstrates promise as a neuroprotective agent, however, its role in humans and in vivo during injury is not fully understood.ObjectiveTo investigate whether elevated levels of ...
David A Paul   +9 more
doaj   +2 more sources

Utility of Cannulated Prolactin to Exclude Stress Hyperprolactinemia in Patients with Persistent Mild Hyperprolactinemia

open access: yesClinical Medicine Insights: Endocrinology and Diabetes, 2021
Background: Stress-induced hyperprolactinemia can be difficult to differentiate from true hyperprolactinema and may result in patients having unnecessary investigations and imaging.
Raya Almazrouei   +3 more
doaj   +1 more source

The brain as a source and a target of prolactin in mammals

open access: yesNeural Regeneration Research, 2022
Prolactin is a polypeptide hormone associated with an extensive variety of biological functions. Among the roles of prolactin in vertebrates, some were preserved throughout evolution.
Ana R Costa-Brito   +2 more
doaj   +1 more source

Gender-specific reference intervals for serum prolactin concentrations before and after precipitation by polyethylene glycol

open access: yesProceedings of Singapore Healthcare, 2022
Prolactin, a hormone secreted by the anterior pituitary, exists in three major forms in circulation. The macroprolactin form is biologically inactive but contributes to elevated serum prolactin concentrations.
Pallavi Chincholkar   +2 more
doaj   +1 more source

Secretion and Function of Pituitary Prolactin in Evolutionary Perspective

open access: yesFrontiers in Neuroscience, 2020
The hypothalamo-pituitary system developed in early vertebrates. Prolactin is an ancient vertebrate hormone released from the pituitary that exerts particularly diverse functions.
Arpád Dobolyi   +8 more
doaj   +1 more source

Prolactin and vitiligo: proposed autocrine/paracrine actions

open access: yesJournal of the Egyptian Women’s Dermatologic Society, 2021
Background The exact cause of vitiligo remains unclear. Several theories have been proposed, including autoimmune and neuroendocrine theories. Prolactin has been studied as an immunomodulatory factor in several autoimmune diseases.
Ghada M El-Hanafy   +3 more
doaj   +1 more source

Metode pembuatan antiprolaktin pada hewan coba kambing lokal sebagai penghambat proses rontok bulu pada ayam arab petelur

open access: yesJournal of Biological Researches, 2012
Anti-prolactin has a specific activity against prolactin. It neutralizes prolactin action in circulation. The effect of such neutralization is the inhibition of feather fall off process, so that hens may be able to produce eggs again. Anti-prolactin can
Erma Safitri
doaj   +1 more source

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