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Prolactin and Autoimmunity [PDF]
Frontiers in Immunology, 2018 The great asymmetry of autoimmune diseases between genders represents one of the most enigmatic observations among the mosaic of autoimmunity. Sex hormones are believed to play a crucial role on this dimorphism. The higher prevalence of autoimmunity among women at childbearing ages, disease onset/relapses during pregnancy, and post-partum are some of ...
Vânia Vieira Borba +5 more
openaire +5 more sources
Clinics in Endocrinology and Metabolism, 1977 Prolactin exists in man as a distinct and separate anterior pituitary hormone from growth hormone. It is important in lactation and the control of gonadal function, although it may have a much wider and basic metabolic role, similar to its role in lower forms. In clinical endocrinology it is important as an index of pituitary and hypothalamic diseases;
A. Renauld +24 more
openaire +4 more sources
Cortisol levels are positively associated with pup-feeding rates in male meerkats [PDF]
, 1980 In societies of cooperative vertebrates, individual differences in contributions to offspring care are commonly substantial. Recent attempts to explain the causes of this variation have focused on correlations between contributions to care and the ...
Carlson, A.A. +6 more
core +6 more sources
Prolactin delays hair regrowth in mice [PDF]
, 2006 Mammalian hair growth is cyclic, with hair-producing follicles alternating between active (anagen) and quiescent (telogen) phases. The timing of hair cycles is advanced in prolactin receptor (PRLR) knockout mice, suggesting that prolactin has a role in ...
Ashby, M.G. +6 more
core +2 more sources
Involvement of miR-106b in tumorigenic actions of both prolactin and estradiol. [PDF]
, 2017 Prolactin promotes a variety of cancers by an array of different mechanisms. Here, we have investigated prolactin's inhibitory effect on expression of the cell cycle-regulating protein, p21.
Bustamante, Karissa +3 more
core +1 more source
To what extent does photoperiod affect cattle reproduction? Clinical perspectives of melatonin administration [PDF]
, 2020 The seasonality of reproduction in most mammals is dictated by photoperiod, temperature and nutrition. Melatonin, mainly synthesized in the pineal gland, is generally accepted as the active mediator of photoperiod responses including reproduction.
De Rensis, F. +3 more
core +1 more source
A novel tilapia prolactin receptor is functionally distinct from its paralog [PDF]
, 2009 A novel tilapia prolactin (PRL) receptor (OmPRLR2) was identified based on its induction during hyperosmotic stress. OmPRLR2 protein shows 28% identity to tilapia OmPRLR1 and 26% identity to human PRLR.
Fiol, Diego Fernando +3 more
core +2 more sources
Prolactin and its receptor as therapeutic targets in glioblastoma multiforme [PDF]
, 2019 Although prolactin (PRL) and its receptor (PRLR) have been detected in glioblastoma multiforme (GBM), their role in its pathogenesis remains unclear. Our aim was to explore their contribution in GBM pathogenesis.
Abt, Araceli +13 more
core +1 more source
Hyperprolactinemia induced by hCG leads to metabolic disturbances in female mice [PDF]
, 2016 The metabolic syndrome is a growing epidemic; it increases the risk for diabetes, cardiovascular disease, fatty liver, and several cancers. Several reports have indicated a link between hormonal imbalances and insulin resistance or obesity.
Bonaventura, Maria Marta +7 more
core +1 more source
Relationship between prolactin plasma levels and white matter volume in women with multiple sclerosis [PDF]
, 2015 BACKGROUND: The role of prolactin (PRL) on tissue injury and repair mechanisms in multiple sclerosis (MS) remains unclear. The aim of this work was to investigate the relationship between PRL plasma levels and brain damage as measured by magnetic ...
Barletta, VALERIA TERESA +10 more
core +4 more sources