Results 1 to 10 of about 92,474 (144)

A long-lasting prolactin stimulates galactopoiesis in mice [PDF]

iScience
Summary: Prolactin is the main hormonal driver of mammalian lactation. To sustain milk production, basal prolactin levels must remain elevated compared to nonpregnant states.
Kasia Kready, Kailyn E. Doiron, Katherine Redfield Chan, Jeffrey C. Way, Quincey Justman, Camille E. Powe, Pamela A. Silver   +6 more
doaj   +2 more sources

Comparison of urinary prolactin and serum/urine prolactin ratio in hyperprolactinemic and macroprolactinemic patients [PDF]

BMC Endocrine Disorders
Background Biologically, the monomeric form of prolactin is the most active. In measurement methods, all forms of prolactin are included in the assay; therefore, the presence of macroprolactin, causes a false increase in prolactin and misdiagnosis of ...
Behnam Ein-Mozaffari, Akbar Aliasgharzadeh, Farzad Najafipour, Azam Moslemi, Mitra Niafar, Vahideh Sadra, Nasser Aghamohammadzadeh, Jalil Houshyar, Halimeh Amirazad   +8 more
doaj   +2 more sources

Bioinspired Prolactin Pulse Release from Responsive Microneedles for Inhibiting Fatty Liver Formation [PDF]

Advanced Science
Hormonal mechanisms of fatty liver formation require in‐depth exploration, and corresponding therapeutic strategies are urgently needed. Here, through serological testing of mice with fatty liver, it is found that the rhythms of prolactin secretion are ...
Hongli Yin, Wenjuan Tang, Danqing Huang, JingJing Gan, Pengzi Zhang, Yuanjin Zhao, Yan Bi   +6 more
doaj   +2 more sources

Prolactin at moderately increased levels confers a neuroprotective effect in non-secreting pituitary macroadenomas.

PLoS ONE, 2022
ContextProlactin, a hormone synthesized by the anterior pituitary gland demonstrates promise as a neuroprotective agent, however, its role in humans and in vivo during injury is not fully understood.ObjectiveTo investigate whether elevated levels of ...
David A Paul, Alejandra Rodrigue, Nicholas Contento, Sam Haber, Ricky Hoang, Redi Rahmani, Adnan Hirad, Ismat Shafiq, Zoë Williams, G Edward Vates   +9 more
doaj   +2 more sources

Utility of Cannulated Prolactin to Exclude Stress Hyperprolactinemia in Patients with Persistent Mild Hyperprolactinemia

Clinical Medicine Insights: Endocrinology and Diabetes, 2021
Background: Stress-induced hyperprolactinemia can be difficult to differentiate from true hyperprolactinema and may result in patients having unnecessary investigations and imaging.
Raya Almazrouei, Shamaila Zaman, Florian Wernig, Karim Meeran   +3 more
doaj   +1 more source

Gender-specific reference intervals for serum prolactin concentrations before and after precipitation by polyethylene glycol

Proceedings of Singapore Healthcare, 2022
Prolactin, a hormone secreted by the anterior pituitary, exists in three major forms in circulation. The macroprolactin form is biologically inactive but contributes to elevated serum prolactin concentrations.
Pallavi Chincholkar, Chin Pin Yeo, Clement Kam Man Ho   +2 more
doaj   +1 more source

The brain as a source and a target of prolactin in mammals

Neural Regeneration Research, 2022
Prolactin is a polypeptide hormone associated with an extensive variety of biological functions. Among the roles of prolactin in vertebrates, some were preserved throughout evolution.
Ana R Costa-Brito, Isabel Gonçalves, Cecília R. A. Santos   +2 more
doaj   +1 more source

Abnormal prolactin secretion is associated with changes in metabolic health biomarkers in acyclic female African elephants (Loxodonta africana)

Theriogenology Wild, 2023
Circulating prolactin aberrations (chronically high or low concentrations) have been shown to have strong associations with ovarian dysfunction in African female elephants.
Natalia A. Prado, Matthew Krcmarik, Steve Paris, Larry, L. Rockwood, Janine L. Brown   +4 more
doaj   +1 more source

Secretion and Function of Pituitary Prolactin in Evolutionary Perspective

Frontiers in Neuroscience, 2020
The hypothalamo-pituitary system developed in early vertebrates. Prolactin is an ancient vertebrate hormone released from the pituitary that exerts particularly diverse functions.
Arpád Dobolyi, Arpád Dobolyi, Szilvia Oláh, Dávid Keller, Rashmi Kumari, Emese A. Fazekas, Vivien Csikós, Éva Renner, Melinda Cservenák   +8 more
doaj   +1 more source

Prolactin and vitiligo: proposed autocrine/paracrine actions

Journal of the Egyptian Women’s Dermatologic Society, 2021
Background The exact cause of vitiligo remains unclear. Several theories have been proposed, including autoimmune and neuroendocrine theories. Prolactin has been studied as an immunomodulatory factor in several autoimmune diseases.
Ghada M El-Hanafy, Olfat G Shaker, Aya Ihab, Heba A Abdelkader   +3 more
doaj   +1 more source