Results 1 to 10 of about 225,617 (369)
Objective: Effects of conventional and atypical antipsychotics on bone mineral density (BMD) and serum prolactin levels (PRL) were examined in patients with schizophrenia.Methods: One hundred and sixty-three first-episode inpatients with schizophrenia ...
Cao, Bingyu+6 more
core +1 more source
Effect of hyperthyroidism on circulating prolactin and hypothalamic expression of tyrosine hydroxylase, prolactin signaling cascade members and estrogen and progesterone receptors during late pregnancy and lactation in the rat [PDF]
Hyperthyroidism (HyperT) compromises pregnancy and lactation, hindering suckling-induced PRL release. We studied the effect of HyperT on hypothalamic mRNA (RT-qPCR) and protein (Western blot) expression of tyrosine hydroxylase (TH), PRL receptor (PRLR ...
Jahn, Graciela Alma+4 more
core +1 more source
Circulating Prolactin Associates With Diabetes and Impaired Glucose Regulation
OBJECTIVE Prolactin is a major stimulus for the β-cell adaptation during gestation and guards postpartum women against gestational diabetes. Most studies of the role of prolactin on glucose metabolism have been conducted in humans and animals during ...
Tiange Wang+11 more
semanticscholar +1 more source
For decades, progesterone and its metabolites have served as the primary biomarkers for monitoring reproductive activity in rhinoceroses, whereas protein hormones have received little attention despite their potential value in understanding reproductive ...
Terri L. Roth+3 more
doaj
Prolactin and cancer: Has the orphan finally found a home?
Prolactin has, for long, been associated with galactorrhea and infertility in women while its role in men is largely unknown. Recently, expression of prolactin in various other tissues like the breast, prostate, decidua, and the brain has been recognized.
Bipin Kumar Sethi+2 more
doaj +1 more source
Stiff Collagen Matrices Increase Tumorigenic Prolactin Signaling in Breast Cancer Cells*
Background: Prolactin, but not its best studied mediator STAT5a, is associated with breast cancer progression. Results: In stiff but not compliant collagen matrices, prolactin promotes tumorigenic processes via an enhanced ERK1/2 cascade.
Craig E. Barcus+3 more
semanticscholar +1 more source
Mutant prolactin receptor and familial hyperprolactinemia.
Hyperprolactinemia that is not associated with gestation or the puerperium is usually due to tumors in the anterior pituitary gland and occurs occasionally in hereditary multiple endocrine neoplasia syndromes. Here, we report data from three sisters with
P. Newey+10 more
semanticscholar +1 more source
Canine pseudopregnancy: an evaluation of prevalence and current treatment protocols in the UK [PDF]
Background: There is a dearth of literature on pseudopregnancy in the bitch, with only a few treatment-based studies published since the 1990s. Pseudopregnancy may be under-recognised in bitches and may account for a proportion of behavioural cases ...
A Bastan+38 more
core +1 more source
Objective: Serum prolactin measurements are important in the differential diagnosis of pituitary masses and subfertility. We observed discrepancies in serum prolactin levels in several patients measured with different immunoassays. Despite differences in
Yanaika S Sabogal Piñeros+4 more
doaj +1 more source
Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse.
Mice carrying a germ-line null mutation of the prolactin receptor gene have been produced by gene targeting in embryonic stem cells. Heterozygous females showed almost complete failure of lactation attributable to greatly reduced mammary gland ...
C. Ormandy+10 more
semanticscholar +1 more source