Results 101 to 110 of about 94,294 (254)
Abstract Aim CD4 + CD25highCD127‐T regulatory cells (Tregs) remain a drug candidate for immunotherapy of type 1 diabetes. We completed three trials testing Tregs in recently diagnosed type 1 diabetes children. Here, we looked for long‐term safety and efficacy aspects important in the authorisation of this therapy.
Marta Bandura +18 more
wiley +1 more source
Effect of opioid(pentazocine) and opioid-antagonist (naloxone) administration on plasma β-LH,FSH and Prolactin(PRL) levels in the perinatal period [PDF]
Jennifer Weil +5 more
openalex +1 more source
Immunomodulatory role of decidual prolactin on the human fetal membranes and placenta [PDF]
Pilar Flores‐Espinosa +8 more
openalex +1 more source
Biochemical and Physiological Effects of Galanin in Health and Disease
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles +3 more
wiley +1 more source
FRI0257 PROLACTIN AND DEHYDROEPIANDROSTERONE SULFATE IN WOMEN WITH ACTIVE SYSTEMIC LUPUS ERYTHEMATOSUS OF RECENT ONSET VERSUS CHRONIC INACTIVE PATIENTS [PDF]
Olga Vera‐Lastra +3 more
openalex +1 more source
Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li +18 more
wiley +1 more source
An overview of the mechanism of action, clinical trials, and classical findings of KarXT for the management of psychotic symptoms in patients with schizophrenia and alzheimer's disease. ABSTRACT Background Acute psychotic symptoms like delusions and hallucinations are of major concern while treating patients with schizophrenia and alzheimer's psychosis,
Ashir Kanwal +7 more
wiley +1 more source
Extrapituitary prolactin promotes generation of Eomes-positive helper T cells mediating neuroinflammation [PDF]
Chenyang Zhang +5 more
openalex +1 more source
Abstract Bexicaserin (LP352) is a selective 5‐hydroxytryptamine 2C (5‐HT2C) superagonist in development for the treatment of seizures in developmental and epileptic encephalopathies (DEEs). This double‐blind, placebo‐controlled, single ascending dose (SAD) Phase 1 study aimed to assess the safety, tolerability, and pharmacokinetic (PK) and ...
Rosa Chan +6 more
wiley +1 more source

