Results 141 to 150 of about 220,665 (364)

Systematic Review and Meta‐Analysis on the Prevalence of Radiotherapy‐Induced Hypopituitarism in Adults With Primary Non‐Pituitary Brain Tumours

open access: yesClinical Endocrinology, Volume 102, Issue 6, Page 683-698, June 2025.
ABSTRACT Context It is well recognised there is a high prevalence of pituitary dysfunction in childhood brain tumours survivors who are treated with radiotherapy. In contrast, the potential for survivors of brain tumours arising in adulthood to develop radiotherapy‐induced hypopituitarism may be underestimated.
Darran Mc Donald   +7 more
wiley   +1 more source

Patient Participation in Urine Specific Gravity Screening for Arginine Vasopressin Deficiency in an Inpatient Neurosurgical Clinic

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Detecting hypotonic urine (specific gravity < 1005 g/L) is crucial for the early identification of arginine vasopressin deficiency (AVP‐deficiency), a common complication after pituitary surgery. This study aimed to evaluate the agreement between urine specific gravity measurements taken by patients using urine test strips and those ...
Jeanne‐Marie Nollen   +7 more
wiley   +1 more source

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan   +14 more
wiley   +1 more source

The Impact of Metformin on Plasma Prolactin Levels in Antipsychotics‐Treated Men With Hyperprolactinemia and Early‐Onset Androgenic Alopecia

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Metformin decreases elevated levels of pituitary hormones. Little is known about the association between the reproductive axis and hormonal effects of this drug. The purpose of our study was to investigate whether activity of the hypothalamic‐pituitary‐gonadal axis determines metformin action on prolactin levels in men with prolactin
Robert Krysiak   +4 more
wiley   +1 more source

Ovarian Endometrioma Disrupts Oocyte‐Cumulus Communication and Mitochondrial Function, With Melatonin Mitigating the Effects

open access: yesCell Proliferation, Volume 58, Issue 4, April 2025.
Diagram illustrating the impact of OEM on oocyte‐cumulus communication, showing reduced TZPs, mitochondrial dysfunction, increased oxidative stress, DNA damage, and apoptosis. Melatonin (MLT) treatment improves communication, enhances mitochondrial function, reduces DNA damage, and restores oocyte quality, offering insights into potential therapeutic ...
Lei Ge   +11 more
wiley   +1 more source

Characterization of Human Pituitary Adenomas in Cell Cultures by Light And Electron Microscopic Morphology And Immunolabeling [PDF]

open access: yes, 2005
The morphology and hormone production of pituitary adenoma cell cultures were compared in order to highlight their characteristic in vitro features. Cell suspensions were prepared from 494 surgical specimens.
Bácsy, Ernő   +6 more
core  

Aetiopathogenesis of infantile epileptic spasms syndrome and mechanisms of action of adrenocorticotrophin hormone/corticosteroids in children: A scoping review

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes   +6 more
wiley   +1 more source

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