Results 211 to 220 of about 88,721 (269)
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American Journal of Obstetrics and Gynecology, 1977
Progesterone (2.5 mg per kilogram) caused sustained hypertension in rabbits. When the same dose of progesterone was administered together with prolactin (1.25 mg. per kilogram), there was no increase in the blood pressure. In rabbits with progesterone-induced hypertension, the addition of prolactin caused a sharp drop in blood pressure. It is suggested
Mati, J K +3 more
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Progesterone (2.5 mg per kilogram) caused sustained hypertension in rabbits. When the same dose of progesterone was administered together with prolactin (1.25 mg. per kilogram), there was no increase in the blood pressure. In rabbits with progesterone-induced hypertension, the addition of prolactin caused a sharp drop in blood pressure. It is suggested
Mati, J K +3 more
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Autoimmunity Reviews, 2012
Sex hormones, especially estrogen and prolactin (PRL), have an important role in modulating the immune response. PRL is secreted from the pituitary gland as well as other organs and cells particularly lymphocytes. PRL has an immune stimulatory effect and promotes autoimmunity.
Shahar, Shelly, Mona, Boaz, Hedi, Orbach
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Sex hormones, especially estrogen and prolactin (PRL), have an important role in modulating the immune response. PRL is secreted from the pituitary gland as well as other organs and cells particularly lymphocytes. PRL has an immune stimulatory effect and promotes autoimmunity.
Shahar, Shelly, Mona, Boaz, Hedi, Orbach
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Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology, 1975
The purification of prolactin is simplified by the strong binding of the hormone to pituitary tissue. An extreme alkaline or acidic pH is required to effectively extract prolactin and this provides a convenient way of removing a large number of serum and pituitary proteins by an initial extraction near neutrality.
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The purification of prolactin is simplified by the strong binding of the hormone to pituitary tissue. An extreme alkaline or acidic pH is required to effectively extract prolactin and this provides a convenient way of removing a large number of serum and pituitary proteins by an initial extraction near neutrality.
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European Journal of Obstetrics & Gynecology and Reproductive Biology, 1981
Hypothyroidism-induced hyperprolactinemia, with or without clinical manifestations, is reported in a short case in addition to the results of basal and thyrotropin-releasing hormone (TRH)-induced prolactin values in primary hypothyroidism. In comparison with an age- and sex-matched group, basal- (P less than 0.02) and TRH-induced (P less than 0.02 ...
L, Van Gaal +3 more
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Hypothyroidism-induced hyperprolactinemia, with or without clinical manifestations, is reported in a short case in addition to the results of basal and thyrotropin-releasing hormone (TRH)-induced prolactin values in primary hypothyroidism. In comparison with an age- and sex-matched group, basal- (P less than 0.02) and TRH-induced (P less than 0.02 ...
L, Van Gaal +3 more
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Metabolism, 1964
Summary The present status of the chemistry of prolactin obtained from ovine pituitary glands has been reviewed. The phenomenon of polymerization of the molecule has been emphasized. Recent experiments resulting in the isolation of monomeric prolactin were described.
J S, DIXON, C H, LI
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Summary The present status of the chemistry of prolactin obtained from ovine pituitary glands has been reviewed. The phenomenon of polymerization of the molecule has been emphasized. Recent experiments resulting in the isolation of monomeric prolactin were described.
J S, DIXON, C H, LI
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Canadian Journal of Physiology and Pharmacology, 1985
This review summarizes evidence suggesting a direct luteotrophic role for the hypophyseal hormone prolactin (PRL). This direct role consists of the capability to stimulate progesterone synthesis in vitro, the capability to maintain the membrane fluidity and receptors for luteinizing hormone and the capability to import substrate for progesterone ...
B D, Murphy, K, Rajkumar
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This review summarizes evidence suggesting a direct luteotrophic role for the hypophyseal hormone prolactin (PRL). This direct role consists of the capability to stimulate progesterone synthesis in vitro, the capability to maintain the membrane fluidity and receptors for luteinizing hormone and the capability to import substrate for progesterone ...
B D, Murphy, K, Rajkumar
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Pituitary, 2008
Medications commonly cause hyperprolactinemia and their use must be differentiated from pathologic causes. The most common medications to cause hyperprolactinemia are the antipsychotic agents, although some of the newer atypical antipsychotics do not do so.
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Medications commonly cause hyperprolactinemia and their use must be differentiated from pathologic causes. The most common medications to cause hyperprolactinemia are the antipsychotic agents, although some of the newer atypical antipsychotics do not do so.
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Seminars in Reproductive Medicine, 2019
AbstractThe relationship between elevated prolactin and infertility has been known for a long time, but the specific mechanism by which prolactin inhibited reproduction had been uncertain. The discovery of kisspeptin has provided novel insights into how prolactin might cause infertility, with extensive evidence that elevated prolactin inhibits ...
David R, Grattan, Raphael E, Szawka
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AbstractThe relationship between elevated prolactin and infertility has been known for a long time, but the specific mechanism by which prolactin inhibited reproduction had been uncertain. The discovery of kisspeptin has provided novel insights into how prolactin might cause infertility, with extensive evidence that elevated prolactin inhibits ...
David R, Grattan, Raphael E, Szawka
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Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology, 1975
The biology of prolactin is reviewed with special emphasis on the fu nctions of prolactin in mammals. The topics of discussion are: 1) cells of origin 2) methods of assay (bioassay luteotropic responses miscellaneous responses radioimmunoassay radioreceptor densitometric measurements) 3) biologic actions (effects related to reproduction growth and ...
A T, Cowie, I A, Forsyth
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The biology of prolactin is reviewed with special emphasis on the fu nctions of prolactin in mammals. The topics of discussion are: 1) cells of origin 2) methods of assay (bioassay luteotropic responses miscellaneous responses radioimmunoassay radioreceptor densitometric measurements) 3) biologic actions (effects related to reproduction growth and ...
A T, Cowie, I A, Forsyth
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Prolactin and the Prolactin Receptor
2001In mammals, prolactin is both an explicit inducer of mammary-gland development and lactation, and an integrator of multiple physiological adaptations during the post-mating phase of the reproductive cycle. These general features of the physiology of mammalian prolactin appear to have evolved from the effects of prolactin on parental physiology and ...
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