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Trends in Endocrinology & Metabolism, 1992
Prolactin (PRL) is one of the most versatile hormones of the pituitary in terms of biologic actions, but how a single molecule is able to evoke so many different responses in the organism is not known. Research in recent years has uncovered a surprising degree of structural polymorphism for PRL, the different forms having variable biopotencies.
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Prolactin (PRL) is one of the most versatile hormones of the pituitary in terms of biologic actions, but how a single molecule is able to evoke so many different responses in the organism is not known. Research in recent years has uncovered a surprising degree of structural polymorphism for PRL, the different forms having variable biopotencies.
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Fertility and Sterility, 1997
To review the pathophysiology, clinical manifestations, current diagnostic procedures, and treatment options for disorders involving PRL production. Common clinical dilemmas are discussed in a pragmatic fashion to guide the practitioner.A world literature search of basic sciences and medical articles from the last three decades was performed using ...
R A, Yazigi, C H, Quintero, W A, Salameh
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To review the pathophysiology, clinical manifestations, current diagnostic procedures, and treatment options for disorders involving PRL production. Common clinical dilemmas are discussed in a pragmatic fashion to guide the practitioner.A world literature search of basic sciences and medical articles from the last three decades was performed using ...
R A, Yazigi, C H, Quintero, W A, Salameh
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New England Journal of Medicine, 1976
Several reports indicate that raised serum prolactin concentrations occur in 15 to 20 per cent of women with amenorrhea1 , 2 and that when the prolactin levels are reduced, normal ovulation cycles and fertility return.3 , 4 Successful management of these cases depends on reliable identification of hyperprolactinemic amenorrhea and accurate diagnosis of
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Several reports indicate that raised serum prolactin concentrations occur in 15 to 20 per cent of women with amenorrhea1 , 2 and that when the prolactin levels are reduced, normal ovulation cycles and fertility return.3 , 4 Successful management of these cases depends on reliable identification of hyperprolactinemic amenorrhea and accurate diagnosis of
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Archiv f�r Gyn�kologie, 1977
Patients with primary infertility due to hyperprolactinemic corpus luteum insufficiency and oligomenorrhea were treated with Bromocriptin. Suppression of serum prolactin for up to four menstrual cycles resulted in a normalisation of the length of the cycle(32 vs 28 days) as well as of luteal progesterone secretion.
H G, Bohnet +3 more
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Patients with primary infertility due to hyperprolactinemic corpus luteum insufficiency and oligomenorrhea were treated with Bromocriptin. Suppression of serum prolactin for up to four menstrual cycles resulted in a normalisation of the length of the cycle(32 vs 28 days) as well as of luteal progesterone secretion.
H G, Bohnet +3 more
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Clinical Obstetrics and Gynecology, 1980
The principal physiologic effect of PRL in human females is the initiation of lactation. The cellular events leading to actual secretion of breast milk are reasonably well defined in the experimental animal. Other than the direct effects on breast tissue in pregnancy, prolactin's role at puberty, during the menstrual cycle, and in pregnancy is poorly ...
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The principal physiologic effect of PRL in human females is the initiation of lactation. The cellular events leading to actual secretion of breast milk are reasonably well defined in the experimental animal. Other than the direct effects on breast tissue in pregnancy, prolactin's role at puberty, during the menstrual cycle, and in pregnancy is poorly ...
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Prolactin stimulation of prolactin receptors in rat liver
Life Sciences, 1975Abstract Hypophysectomy of the female rat results in a loss of prolactin receptors from the liver. Seventy percent of specific prolactin binding is lost within 24 hours; by 48 hours receptor levels are less than 5% of those found in livers from intact rats.
M E, Costlow, R A, Buschow, W L, McGuire
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Pituitary production of prolactin and prolactin-suppressing drugs
Lupus, 2001Prolactin secretion from the anterior pituitary is mediated via dopaminergic pathways. Any process that alters dopamine production or transport in the central nervous system may lead to hyperprolactinemia. Most cases of hyperprolactinemia are due to prolactin secreting pituitary tumors or to medications which alter dopamine production.
M J, Tansey, J A, Schlechte
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Endocrine, 1995
We have described the expression of the prolactin (PRL) gene and the occurrence of PRL-like immunoreactive proteins in the hypothalamic-neurophypophyseal system of the rat. Here, we investigated the nature of neurohypophyseal PRL-like antigens, by studying the biological activity of medium conditioned by incubated neurohypophyses in specific bioassays ...
F J, López-Gómez +4 more
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We have described the expression of the prolactin (PRL) gene and the occurrence of PRL-like immunoreactive proteins in the hypothalamic-neurophypophyseal system of the rat. Here, we investigated the nature of neurohypophyseal PRL-like antigens, by studying the biological activity of medium conditioned by incubated neurohypophyses in specific bioassays ...
F J, López-Gómez +4 more
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PROLACTIN RESPONSE TO HYPOGLYCÆMIA
The Lancet, 1973info:eu-repo/semantics ...
Copinschi, Georges +7 more
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