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Prolactin and immunomodulation
The American Journal of Medicine, 1993To review the recent exploration of the role of prolactin in immune function.Studies published that were identified through a MEDLINE search as well as through the bibliographies of those articles enumerated.Both humoral and cell-mediated immunity are compromised in hypophysectomized rats. The reintroduction of prolactin to these animals restores their
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Autoimmunity Reviews, 2002
Prolactin (PRL) is a versatile hormone that is produced by the anterior pituitary gland and various extrapituitary sites including immune cells. Furthermore, PRL has widespread influences on proliferation and differentiation of a variety of cells in the immune system and is, in effect, a cytokine.
Olga, Vera-Lastra +2 more
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Prolactin (PRL) is a versatile hormone that is produced by the anterior pituitary gland and various extrapituitary sites including immune cells. Furthermore, PRL has widespread influences on proliferation and differentiation of a variety of cells in the immune system and is, in effect, a cytokine.
Olga, Vera-Lastra +2 more
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American Journal of Psychiatry, 1981
Prolactin is a protein hormone synthesized and secreted by the anterior pituitary gland. Because the monoamines dopamine and serotonin are important in the control of its secretion, prolactin has been the subject of much psychoendocrine research in recent years.
J R, de la Fuente, A H, Rosenbaum
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Prolactin is a protein hormone synthesized and secreted by the anterior pituitary gland. Because the monoamines dopamine and serotonin are important in the control of its secretion, prolactin has been the subject of much psychoendocrine research in recent years.
J R, de la Fuente, A H, Rosenbaum
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Clinical Reviews in Allergy & Immunology, 2009
The relationship between prolactin and the immune system has been demonstrated in the last two decades, opening new windows in the field of the immunoendocrinology. Prolactin has an important role in the innate and adaptive immune response. Increased prolactin levels have been described in autoimmune diseases such as systemic lupus erythematosus ...
Luis J, Jara +4 more
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The relationship between prolactin and the immune system has been demonstrated in the last two decades, opening new windows in the field of the immunoendocrinology. Prolactin has an important role in the innate and adaptive immune response. Increased prolactin levels have been described in autoimmune diseases such as systemic lupus erythematosus ...
Luis J, Jara +4 more
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Trends in Endocrinology & Metabolism, 1992
Prolactin (PRL) is one of the most versatile hormones of the pituitary in terms of biologic actions, but how a single molecule is able to evoke so many different responses in the organism is not known. Research in recent years has uncovered a surprising degree of structural polymorphism for PRL, the different forms having variable biopotencies.
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Prolactin (PRL) is one of the most versatile hormones of the pituitary in terms of biologic actions, but how a single molecule is able to evoke so many different responses in the organism is not known. Research in recent years has uncovered a surprising degree of structural polymorphism for PRL, the different forms having variable biopotencies.
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Fertility and Sterility, 1997
To review the pathophysiology, clinical manifestations, current diagnostic procedures, and treatment options for disorders involving PRL production. Common clinical dilemmas are discussed in a pragmatic fashion to guide the practitioner.A world literature search of basic sciences and medical articles from the last three decades was performed using ...
R A, Yazigi, C H, Quintero, W A, Salameh
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To review the pathophysiology, clinical manifestations, current diagnostic procedures, and treatment options for disorders involving PRL production. Common clinical dilemmas are discussed in a pragmatic fashion to guide the practitioner.A world literature search of basic sciences and medical articles from the last three decades was performed using ...
R A, Yazigi, C H, Quintero, W A, Salameh
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New England Journal of Medicine, 1976
Several reports indicate that raised serum prolactin concentrations occur in 15 to 20 per cent of women with amenorrhea1 , 2 and that when the prolactin levels are reduced, normal ovulation cycles and fertility return.3 , 4 Successful management of these cases depends on reliable identification of hyperprolactinemic amenorrhea and accurate diagnosis of
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Several reports indicate that raised serum prolactin concentrations occur in 15 to 20 per cent of women with amenorrhea1 , 2 and that when the prolactin levels are reduced, normal ovulation cycles and fertility return.3 , 4 Successful management of these cases depends on reliable identification of hyperprolactinemic amenorrhea and accurate diagnosis of
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Archiv f�r Gyn�kologie, 1977
Patients with primary infertility due to hyperprolactinemic corpus luteum insufficiency and oligomenorrhea were treated with Bromocriptin. Suppression of serum prolactin for up to four menstrual cycles resulted in a normalisation of the length of the cycle(32 vs 28 days) as well as of luteal progesterone secretion.
H G, Bohnet +3 more
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Patients with primary infertility due to hyperprolactinemic corpus luteum insufficiency and oligomenorrhea were treated with Bromocriptin. Suppression of serum prolactin for up to four menstrual cycles resulted in a normalisation of the length of the cycle(32 vs 28 days) as well as of luteal progesterone secretion.
H G, Bohnet +3 more
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Clinical Obstetrics and Gynecology, 1980
The principal physiologic effect of PRL in human females is the initiation of lactation. The cellular events leading to actual secretion of breast milk are reasonably well defined in the experimental animal. Other than the direct effects on breast tissue in pregnancy, prolactin's role at puberty, during the menstrual cycle, and in pregnancy is poorly ...
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The principal physiologic effect of PRL in human females is the initiation of lactation. The cellular events leading to actual secretion of breast milk are reasonably well defined in the experimental animal. Other than the direct effects on breast tissue in pregnancy, prolactin's role at puberty, during the menstrual cycle, and in pregnancy is poorly ...
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Prolactin stimulation of prolactin receptors in rat liver
Life Sciences, 1975Abstract Hypophysectomy of the female rat results in a loss of prolactin receptors from the liver. Seventy percent of specific prolactin binding is lost within 24 hours; by 48 hours receptor levels are less than 5% of those found in livers from intact rats.
M E, Costlow, R A, Buschow, W L, McGuire
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