Results 1 to 10 of about 8,469 (207)

Wogonin inhibits the proliferation of prolactinoma through the PI3K/AKT signaling pathway [PDF]

Frontiers in Pharmacology
ObjectivesThis investigation sought to explore the inhibitory impact of wogonin on prolactinoma and elucidate its underlying mechanisms through network pharmacology, molecular docking (MD), and molecular biology experiments.MethodsTarget identification ...
Zhiyong Du, Zhiyong Du, Zhiyong Du, Zhiyong Du, Cuiping Sun, Cuiping Sun, Cuiping Sun, Cuiping Sun, Jiawei Wu, Jiawei Wu, Hongwei Gao, Hongwei Gao, Hongwei Gao, Hongwei Gao, Jialong Wu, Jialong Wu, Jialong Wu, Jialong Wu, You Zhou, You Zhou, You Zhou, You Zhou, Xuechao Wu, Xuechao Wu, Liping Shen, Liping Shen, Qing Wang, Qing Wang, Qing Wang, Qing Wang   +29 more
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Prolactinoma presenting as chronic anaemia with osteoporosis: a case report [PDF]

Journal of Medical Case Reports, 2010
Introduction Unexplained anaemia is a rare mode of presentation for prolactinoma. We describe a case of a man, with chronic anaemia ascribed to old age.
Hanley John P, MacLean Fergus R
doaj   +2 more sources

MicroRNA networks in prolactinoma tumorigenesis: a scoping review [PDF]

Cancer Cell International
Background Prolactinoma is the leading type of pituitary adenoma. Aside from the mass-like effect of prolactinoma, its hormonal effect is the main pathological cause of endocrine dysregulation and infertility.
Sevil Ghaffarzadeh Rad, Fatemeh Nejadi Orang, Mahdi Abdoli Shadbad   +2 more
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Exploring retinal vessel density alterations in prolactinoma patients: Insights from OCTA imaging [PDF]

Indian Journal of Ophthalmology
Purpose: To investigate microvascular changes in the macular and peripapillary area in prolactinoma patients by using optical coherence tomography angiography (OCTA). Design: A retrospective study.
Serife Ciloglu Hayat, Yusuf Cem Yilmaz, Merve Kelebek, Esra Hatipoglu   +3 more
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Transcriptomic analysis of the anti-tumor effects of leflunomide in prolactinoma [PDF]

Scientific Reports
Leflunomide’s anti-tumor effects have been investigated in various types of tumors; however, its impact on pituitary adenoma, particularly prolactinoma, is unclear.
Xiangdong Pei, Yuyang Peng, Huachun Yin, Zhenle Zang, Kaifeng Shen, Song Li, Chunqing Zhang   +6 more
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Giant prolactinoma with progressive cranial settling and central herniation: a case report [PDF]

Journal of Medical Case Reports
Background Giant prolactinoma (size > 4 cm) is a rare condition and accounts for less than 1% of pituitary adenomas. In even rarer cases, these lesions may involve craniocervical structures requiring surgical intervention. The present case is the largest
Taha Shahbazi, Soheil Abdollahi Yeganeh, Shiva Borzouei, Mahdi Arjipour   +3 more
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Cholesterol-activated stress granules reduce the membrane localization of DRD2 and promote prolactinoma dopamine agonists resistance [PDF]

Acta Neuropathologica Communications
Prolactinoma is the most prevalent pituitary neuroendocrine tumor and dopamine agonists (DAs) targeting dopamine D2 receptor (DRD2) are recommended as the first-line treatment. However, varying degrees of DA resistance limit patient benefit.
Yuyang Peng, Huachun Yin, Xiangdong Pei, Yuan Zhang, Chengcheng Wang, Xin Zheng, Hong Liang, Hui Yang, Song Li   +8 more
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Descriptive Epidemiology and Survival Analysis of Prolactinomas and Cushing’s Disease in Korea [PDF]

Endocrinology and Metabolism, 2021
Background Only a few studies have established the epidemiology of prolactinoma and Cushing’s disease in Korea. Furthermore, the incidence of these disease are increasing than before associated with the development of technologies.
Jin Sun Park, Soo Jin Yun, Jung Kuk Lee, So Young Park, Sang Ouk Chin   +4 more
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The Effect of Prolactinoma on Tear Film Function

Türk Oftalmoloji Dergisi, 2022
Objectives:To compare dry eye parameters in prolactinoma patients and healthy controls and evaluate their correlation with prolactin (PRL) levels and the duration of hyperprolactinemia.Materials and Methods:Consecutive patients with prolactinoma and ...
Cezmi Doğan, Ümit Yaşar Güleser, Oğuzhan Kılıçarslan, Burak Mergen, Özer Açbay, Güzin İskeleli   +5 more
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Inhibiting MAPK14 showed anti-prolactinoma effect

BMC Endocrine Disorders, 2020
Background The specific underlying pathogenesis of prolactinoma has not been clarified yet, to the best of our knowledge. p38 mitogen-activated protein kinase (MAPK) signaling including p38α MAPK (MAPK14), p38β (MAPK11), p38γ (MAPK12) and p38δ (MAPK13 ...
Qiao-yan Ding, Yu Zhang, Li Ma, Yong-gang Chen, Jin-hu Wu, Hong-feng Zhang, Xiong Wang   +6 more
doaj   +1 more source