Results 11 to 20 of about 5,707 (185)
Hyperprolactinemia, defined by a level of serum prolactin above the standard upper limit of normal range, is a common finding in clinical practice and prolactinomas are the main pathological cause. Prolactinomas lead to signs and symptoms of hormone oversecretion, such as galactorrhea and hypogonadism, as well as symptoms of mass effect, including ...
Luiz Eduardo Wildemberg +2 more
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Pituitary Tumour Apoplexy as Cause of Death of Simonetta Vespucci, the Venus by Botticelli. [PDF]
A reassessment of Simonetta Vespucci, muse of Sandro Botticelli, attributes her long‐mysterious death to a pituitary adenoma. Clinical reinterpretation of historical accounts suggests tumour expansion led to sellar destruction, severe haemorrhage, and pulmonary complications, offering a coherent medical explanation for her sudden death at twenty‐three.
Nardelli D +3 more
europepmc +2 more sources
Prolactinomas are the commonest form of pituitary neuroendocrine tumor (PitNET), representing approximately half of such tumors. Dopamine agonists (DAs) have traditionally been the primary treatment for the majority of prolactinomas, with surgery considered the second line.
Inder, Warrick J., Jang, Christina
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Os prolactinomas são os adenomas de hipófise mais comuns e frequentemente afetam mulheres jovens, em faixa etária de fertilidade. A hiperprolactinemia causa hipogonadismo, irregularidade menstrual ou amenorreia em mulheres, níveis baixos de testosterona sérica em homens e infertilidade e disfunção sexual em ambos os gêneros.
Glezer, Andrea, Bronstein, Marcello D.
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Objectives To investigate the expression levels of aromatase cytochrome P450 enzyme (P450AROM) and related molecules—estrogen receptor-beta (ER-β), Ki-67, and p53—in prolactinoma tumor tissue from pre- and post-menopausal women, and to determine the ...
Yin-Xia Su +9 more
doaj +1 more source
Prolactinoma presenting as chronic anaemia with osteoporosis: a case report
Introduction Unexplained anaemia is a rare mode of presentation for prolactinoma. We describe a case of a man, with chronic anaemia ascribed to old age.
Hanley John P, MacLean Fergus R
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Instruction: The current study reports a woman with pituitary adenoma and frontal convexity meningioma that was detected accidentally. To the best of our knowledge, this case is considered as a rare clinical scenario.
Thi Phuong Hoai Dinh +2 more
doaj +1 more source
Anti-c-myc efficacy block EGFL7 induced prolactinoma tumorigenesis
Resistance to Dopamine agonists therapy is still a key factor that hinders the clinical treatment of prolactinoma. Consequently, a large number of investigations have been carried out to identify novel therapeutic targets.
Lan Xiaolei +4 more
doaj +1 more source
Management of prolactinoma in pregnancy is a big challenge for the treating obstetrician as prolactin levels are normally raised in pregnancy and this creates a possibility of missing the diagnosis of prolactinoma.
Sukhwinder Kaur Bajwa +3 more
doaj +1 more source
Cabergoline has long been used in the medical management of prolactin-secreting pituitary adenomas. However, there is contradicting and inadequate evidence on the efficacy of cabergoline in achieving radiological and biochemical remission in prolactinoma.
Rakesh Mishra +5 more
doaj +1 more source

