Results 71 to 80 of about 10,221 (208)

Alcohol and the endocrine system: A critical review of disruptions, potential mechanisms, and health implications

Alcohol, Clinical and Experimental Research, Volume 50, Issue 1, January 2026.
The endocrine system coordinates whole body cellular function and maintains homeostasis. Alcohol impacts the integrity of endocrine regulation at multiple sites, contributing to risk for comorbidities. Some of the alcohol‐mediated pathophysiological effects on the endocrine system include alterations in receptor expression and responsiveness, protein ...
Patricia E. Molina, Liz Simon
wiley   +1 more source

Adrenal Crisis Induced by Zoledronic Acid in Two Patients With Hypopituitarism: A Case Report and Literature Review

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Adrenal insufficiency (AI) is characterized by inadequate steroid hormone production and is frequently a consequence of hypopituitarism, which is also associated with increased risk of osteoporosis due to deficiencies in growth hormone, gonadotropins, and other pituitary hormones.
Abrar Mohammed AlFaifi, Wael Mohammad AlMistehi, Osamu Isozaki   +2 more
wiley   +1 more source

miR‐221/222 Facilitate Pituitary Adenoma Progression Via PHACTR4 Downregulation

Human Mutation, Volume 2026, Issue 1, 2026.
Most of pituitary adenomas are biologically benign, but some grow local‐invasively and can invade important adjacent tissues, resulting in clinical symptoms such as hormone secretion disorders and visual field defects. MicroRNA‐221/222 (miR‐221/222) is tandemly encoded on the X chromosome in humans, mice and rats, and is highly conserved in vertebrates
Wenjing Dong, Shiju Yan, Lingyun Song, Wei Wang, Di Sun, Ping Pang, Guoqing Yang, Weijun Gu, Sujit Nair   +8 more
wiley   +1 more source

Epidemiologia dos cancros colorectal e do estômago no sul de Portugal:um contributo da modelação estatística em dados oncológicos [PDF]

, 2016
O peso que as neoplasias do estômago, cólon e reto assumem na sociedade portuguesa, em particular na região sul de Portugal, foi um dos elementos que motivou o presente estudo que tem por objetivo analisar tendências, projeções, sobrevivências relativas ...
São João, Ricardo
core  

Treatment-resistant pediatric giant prolactinoma and multiple endocrine neoplasia type 1 [PDF]

, 2015
Background Pediatric pituitary adenomas are rare, accounting for  A) being eventually identified in intron 4 of the MEN1 gene, potentially explaining the difficulties in management of this tumor.
Bulwer, C, Gan, H-W, Jeelani, O, Korbonits, M, Levine, MA, Spoudeas, HA   +5 more
core   +1 more source

Ept7, a quantitative trait locus that controls estrogen-induced pituitary lactotroph hyperplasia in rat, is orthologous to a locus in humans that has been associated with numerous cancer types and common diseases. [PDF]

PLoS ONE, 2018
Pituitary adenoma is a common intracranial neoplasm that is observed in approximately 10% of unselected individuals at autopsy. Prolactin-producing adenomas, i.e., prolactinomas, comprise approximately 50% of all pituitary adenomas and represent the most
Kirsten L Dennison, Aaron C Chack, Maureen Peters Hickman, Quincy Eckert Harenda, James D Shull   +4 more
doaj   +1 more source

Treatment Outcomes of Lobular Granulomatous Mastitis: Impact of Hyperprolactinemia, Diabetes, and Erythema Nodosum—Insights From a 7‐Year Cohort Study

The Breast Journal, Volume 2026, Issue 1, 2026.
Background This study presents our observations on the management and follow‐up of patients diagnosed with lobular granulomatous mastitis (LGM) in a cohort study. Additionally, characteristics associated with a longer disease course, as well as treatment challenges in patients with erythema nodosum, diabetes, and hyperprolactinemia, would be discussed.
Mina AkbariRad, Fereshte Sheybani, Abdollah Firoozi, Samaneh Sajjadi, Maryam Emadzadeh, Marzieh Kazerani, Sajad Ataei Azimi, Mahdieh Mottaghi, Imtiaz Wani   +8 more
wiley   +1 more source

Trial Readiness: Understanding the Natural History of Rare Diseases

Journal of Inherited Metabolic Disease, Volume 48, Issue 6, November 2025.
ABSTRACT Inherited metabolic diseases (IMD) represent the largest and still growing group of treatable genetic disorders and are increasingly amenable to targeted interventions that achieve varying degrees of prognostic improvement. Innovative therapies are on the horizon and offer promising opportunities for disease‐changing treatment for a variety of
Thomas Opladen, Ulrike Mütze, Florian Gleich, Sven F. Garbade, Oya Kuseyri Hübschmann, Matthias Zielonka, Stefan Kölker   +6 more
wiley   +1 more source

MicroRNA networks in prolactinoma tumorigenesis: a scoping review

Cancer Cell International
Background Prolactinoma is the leading type of pituitary adenoma. Aside from the mass-like effect of prolactinoma, its hormonal effect is the main pathological cause of endocrine dysregulation and infertility.
Sevil Ghaffarzadeh Rad, Fatemeh Nejadi Orang, Mahdi Abdoli Shadbad   +2 more
doaj   +1 more source

Successful treatment of a prolactinoma with the antipsychotic drug aripiprazole

Endocrinology, Diabetes & Metabolism Case Reports, 2016
In this report, we describe a female patient with both prolactinoma and psychotic disorder who was successfully treated with aripiprazole, a partial dopamine 2 receptor agonist.
Ilse C A Bakker, Chris D Schubart, Pierre M J Zelissen   +2 more
doaj   +1 more source