Results 61 to 70 of about 3,096 (170)

Integrating Human Intestinal Organoids into FDA's New Approach Methodologies for Drug Discovery

Advanced Science, Volume 13, Issue 20, 9 April 2026.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra, Ibrahim M. Sayed, Souhrid Mukherjee, Honit Piplani, Aida Habtezion, Michael J. Rosen, Jospeh C. Wu   +6 more
wiley   +1 more source

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

Pediatric Blood &Cancer, Volume 73, Issue 5, May 2026.
Gabriele Mortari, Caterina Costagliola, Marta Nebiolo, Francesca Parisi, Martina Morini, Katia Mazzocco, Gabriele Gaggero, Stefano Volpi, Stefania Sorrentino, Virginia Livellara   +9 more
wiley   +1 more source

Natural Remedies for Gut Health: The Role of Plant Extracts in Combating Inflammatory Bowel Disease and Colon Cancer

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Created in BioRender. Haralambie, O. (2025) https://BioRender.com/dh5ly89. ABSTRACT Digestive disorders such as inflammatory bowel disease (IBD) and colorectal cancer are among the most significant global health challenges, largely driven by chronic inflammation and oxidative stress.
Oana‐Roxana Haralambie, Sanda Andrei
wiley   +1 more source

Advancing the Diagnosis of Non‐Hodgkin Lymphoma Through Next‐Generation Sequencing in Developing Countries: An Evaluation of Progress—A Narrative Review

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Non‐Hodgkin lymphoma (NHL) is the most prevalent hematological malignancy worldwide and accounts for approximately 3% of all cancer cases and fatalities. Next‐generation sequencing (NGS) has advanced molecular diagnosis and targeted treatment in developed countries.
Mohammadreza Saeidnia, Mehdi Shokri, Hassan Nourmohammadi, Safa Radmehr, Mashallah Babashahi, Mohamad Moradi, Maryam Karimian, Mohammad Panji, Elahe Motevaseli   +8 more
wiley   +1 more source

In-feed macrolide Leucomycin (Leucomag 30% PR) for prevention of proliferative enteropathy in experimentally infected pigs Ração medicada com Leucomicina (Leucomag 30% PR) para prevenção da enteropatia proliferativa em leitões experimentalmente infectados

Ciência Rural, 2010
The aim of this study was to evaluate the efficacy of orally administered leucomycin at 90 and 180ppm for the prevention of porcine proliferative enteropathy (PPE) in experimentally infected pigs. A total of 90 commercial five-week-old pigs were randomly
Silvia de Araújo França, Glauber de Souza Machado, Paulo Roberto Andreoli, Julio César Borges Santos, Roberto Maurício Carvalho Guedes   +4 more
doaj  

New Method for Lawsonia intracelullaris Quantification Based on Optical Density by Spectrophotometry

Microorganisms
Studies investigating the pathogenesis of Lawsonia intracellularis often require bacterial quantification in suspension. However, due to the organism’s fastidious growth requirements—being both intracellular and microaerophilic—traditional quantification
Mirtha E. Suarez-Duarte, Ricardo P. Laub, Renato L. Santos, Carlos E. R. Pereira, Talita P. Resende, Matheus D. Araujo, Paula A. Correia, Jessica C. R. Barbosa, Roberto M. C. Guedes   +8 more
doaj   +1 more source

Diagnóstico histoquímico e imunoistoquímico da enteropatia proliferativa (Lawsonia intracellularis) em suínos Detection of swine proliferative enteropathy (Lawsonia intracellularis) in slaughtered pigs by histochemical and immunohistochemical techniques

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2005
Estudou-se a eficácia do diagnóstico macroscópico de lesões da enteropatia proliferativa suína (EPS) usando-se fragmentos de íleo de 663 suínos, coletados em abatedouros localizados em três municípios do Rio Grande do Sul.
G.S. Faccini, R.M.C. Guedes, C.A. Pescador, C.E.F. Cruz, D. Driemeier   +4 more
doaj   +1 more source

Evidence of host adaptation in Lawsonia intracellularis infections

Veterinary Research, 2012
Background Lawsonia intracellularis is the causative agent of proliferative enteropathy, an endemic disease in pigs and an emerging concern in horses. Enterocyte hyperplasia is a common lesion in every case but there are differences regarding clinical ...
Vannucci Fabio A, Pusterla Nicola, Mapes Samantha M, Gebhart Connie   +3 more
doaj   +1 more source

Tylosin injectable for the treatment of porcine proliferative enteropathy in experimentally inoculated pigs

Pesquisa Veterinária Brasileira
: Porcine proliferative enteropathy (PPE) is one of the most common enteric diseases in growing and finishing pigs. PPE is characterized by reduced growth performance, accompanied or not by diarrhea.
Luisa V.A. Otoni, Michelle P. Gabardo, Núbia R. Macêdo, Mariane M. Wagatsuma, Marina M. Pereira, Roberto Maurício C. Guedes   +5 more
doaj   +1 more source

Prevalence of equine proliferative enteropathy in Hidaka district, Hokkaido, over five seasons. [PDF]

J Equine Sci, 2022
Niwa H, Higuchi T, Fujii S, Kinoshita Y, Uchida-Fujii E, Sueyoshi M, Nukada T, Ueno T.   +7 more
europepmc   +1 more source