Results 191 to 200 of about 303,245 (307)

Entdeckung eines antiviralen Elektronentransferprozesses zur Erzeugung katalytisch selbstversorgender viraler Restriktionsfaktoren

Angewandte Chemie, EarlyView.
CYB5R3 wird als mutmaßlicher Elektronentransferpartner von Viperin (RSAD2) identifiziert, was erklärt, warum die ER‐Lokalisation für die antivirale Aktivität erforderlich ist. Dieses Wissen ermöglichte die Entwicklung immunstiller, katalytisch selbstversorgender antiviraler Restriktionsfaktor‐Enzyme (iCAREs), die ein antivirales Nukleosidtriphosphat ...
Mengdi Wu, Nghi Thao Hoang, Deborah Grifagni, Meritxell Wu‐Lu, Yujie Sheng, Theo Situmorang, Pei‐Hsin Tai, Zheng Chen, Astrid Maluta, Mohammed Hakil, Bianca Susini, Hannah Florance, Peter‐Leon Hagedoorn, John Mark Sutton, Maria‐Andrea Mroginski, Simone Ciofi‐Baffoni, Kourosh H. Ebrahimi   +16 more
wiley   +1 more source

Cultivar differences in heat tolerance of <i>Oncidium</i> orchids: physiological mechanisms and implications for breeding strategies. [PDF]

Front Plant Sci
Luo X, Hong X, Luo Y, Yi S, Yu X, Li C, Liao Y, Zhang M, Lu S.   +8 more
europepmc   +1 more source

A zero-parameter first-principles gate framework for full-length TP53 missense variant interpretation. [PDF]

PLoS Comput Biol
Iizumi M.
europepmc   +1 more source

Impaired P4HA1-Driven Hydroxyproline Formation Mediates Scleral Collagen Disruption in Form-Deprivation Myopia. [PDF]

Invest Ophthalmol Vis Sci
Li J, Feng J, Han Y, Gong X, Li S, Tang G, Liu Y, Wang J, Dong X, Yin Y, Xie Y, Bi H, Song J.   +12 more
europepmc   +1 more source

Plug-and-play - enzymatic amino acid production from methanol and carbon dioxide. [PDF]

Nat Commun
Willers VP, Lehmann V, Müller S, Vogelgsang F, Roth A, Blombach B, Pick A, Sieber V.   +7 more
europepmc   +1 more source

Discovery of an Antiviral Electron Transfer Process to Create Catalytically Self‐Sufficient Viral Restriction Factors

Angewandte Chemie International Edition, EarlyView.
CYB5R3 is identified as a putative electron‐transfer partner of viperin (RSAD2), explaining why ER localisation is required for antiviral activity. Its utilisation enabled the engineering of immune‐silent, catalytically self‐sufficient antiviral restriction factor enzymes (iCAREs) that produce an antiviral nucleoside triphosphate analogue (ANTA ...
Mengdi Wu, Nghi Thao Hoang, Deborah Grifagni, Meritxell Wu‐Lu, Yujie Sheng, Theo Situmorang, Pei‐Hsin Tai, Zheng Chen, Astrid Maluta, Mohammed Hakil, Bianca Susini, Hannah Florance, Peter‐Leon Hagedoorn, John Mark Sutton, Maria‐Andrea Mroginski, Simone Ciofi‐Baffoni, Kourosh H. Ebrahimi   +16 more
wiley   +1 more source

Proline biosynthesis in a proline-accumulating barley mutant [PDF]

, 1984
Bright, S. W. J., Smith, S. J., Hill, J. M., Kueh, J. S. H.   +3 more
core   +1 more source

Effect of Horizontal Transfer of Cold-Tolerant Substances of <i>Ambrosia artemisiifolia</i> on the Low Temperature Adaptability of <i>Ophraella communa</i>. [PDF]

Insects
Wang X, He M, Yang L, Zhang Y, Yang J, Zhang X, Zhou Z.   +6 more
europepmc   +1 more source

Prolin [PDF]

, 2017
openaire   +1 more source

Physiological and Biochemical Responses of Two Major Legume Crops to Seed Priming-A Systematic Review. [PDF]

Plants (Basel)
Ngcungama L, Figlan S, Sibisi PP, Mutanda M, Msomi M.   +4 more
europepmc   +1 more source