ABSTRACT Improving cell‐specific productivity remains a central objective in biopharmaceutical manufacturing. In this study, the effect of blue light illumination on IgG1‐producing CHO DP‐12 cells was systematically evaluated across batch, fed‐batch, and perfusion cultivations in controlled 3 L bioreactor systems.
Stefanie Föller +2 more
wiley +1 more source
Plasma 4-Hydroxyproline Levels Are Associated with Diabetes in Chinese Adults: A Cross-Sectional Analysis. [PDF]
Huang Q +8 more
europepmc +1 more source
Microbial Hydrolysates as Amino Acid Source in Cell Culture Media for Cellular Agriculture
ABSTRACT The high cost of cultivation media remains one of the barriers to the commercialization of cultivated meat. Current serum‐free media reduce reliance on fetal bovine serum but only achieve modest cost savings. Especially at larger scales (> 20 m3), pharmaceutical‐grade amino acids and recombinant proteins remain major cost drivers.
Jelle C. Hoek +3 more
wiley +1 more source
Halotolerant <i>Kocuria</i> and <i>Bacillus</i> species enhanced saline-alkaline stress tolerance in foxtail millet. [PDF]
Ko CN, Lee TY, Lin WY.
europepmc +1 more source
These results demonstrate that mixotrophic conditions drive both microbial community shifts and metabolic reprogramming, underscoring the importance of cultivation strategy and polyculture selection for targeted applications such as nutrient recovery and bioproduct generation.
Quyen Nham +3 more
wiley +1 more source
Enhanced Endogenous GABA Biosynthesis Modifies Fruit Production and GABA Accumulation in a Medium-Sized Tomato Cultivar Under Salt Stress. [PDF]
Suzuki T, Takayama M, Ezura H.
europepmc +1 more source
Atomically precise metal cluster enzymes for pathological tissue regeneration
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong +11 more
wiley +1 more source
Jasmonic acid and engineered dog manure biochar improve salinity tolerance in <i>Phaseolus vulgaris</i> through coordinated hormonal, antioxidant, and root responses. [PDF]
Murtaza G +7 more
europepmc +1 more source
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang +9 more
wiley +1 more source
Assessment of the Potential of Bitter Melon (<i>Momordica charantia</i>) and Squash (<i>Cucurbita pepo</i>) as Rootstocks for Enhancing Drought Tolerance in Cucumber. [PDF]
Kacar A +6 more
europepmc +1 more source

