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Glucose is dynamically regulated by time of day in humans and Drosophila. [PDF]

open access: yesPLoS Biol
Malik DM   +11 more
europepmc   +1 more source
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LC-MS/MS method for proline-glycine-proline and acetylated proline-glycine-proline in human plasma

Journal of Chromatography B, 2023
The extracellular cellular matrix (ECM) maintains tissue structure and regulates signaling functions by continuous degradation and remodeling. Inflammation or other disease conditions activate proteases including matrix metalloproteinases (MMPs) that degrade ECM proteins and in particular generate fragments of collagen and elastin, some of which are ...
Ekta Tiwary   +5 more
openaire   +2 more sources

Proline Analogues

Chemical Reviews
Within the canonical repertoire of the amino acid involved in protein biogenesis, proline plays a unique role as an amino acid presenting a modified backbone rather than a side-chain. Chemical structures that mimic proline but introduce changes into its specific molecular features are defined as proline analogues.
Marina Rubini, Vladimir Kubyshkin
exaly   +3 more sources

Control of Proline Biosynthesis by Proline and Proline Analogues

Nature, 1966
MICRO-ORGANISMS prevent over-production of amino -acids by two mechanisms: (a) end-product inhibition of the action of the first specific enzyme in the biosynthetic sequence, and (b) inhibition of the synthesis of all the enzymes in the sequence (enzyme repression)1,2. A number of growth-inhibitory analogues of normal protein amino-acids, besides being
H, Tristram, C F, Thurston
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Proline and proline derivatives as anticonvulsants

General Pharmacology: The Vascular System, 1989
1. The anticonvulsant properties of L-proline, of proline derivatives (trans-4-hydroxy-L-proline, cis-4-hydroxy-D-proline, 3,4-dehydro-D,L-proline) and of D- and L-pipecolic acid were studied alone and in combination with vigabatrin (R/S-4-aminohex-5-enoic acid).
S, Sarhan, N, Seiler
openaire   +2 more sources

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