Results 101 to 110 of about 658,113 (299)

Cognitive–behavioural conjoint therapy versus prolonged exposure for PTSD in military service members and veterans: results and lessons from a randomized controlled trial

open access: yesEuropean Journal of Psychotraumatology
Background: Military personnel and veterans are at heightened risk for exposure to traumatic events and posttraumatic stress disorder (PTSD), as well as intimate relationship problems associated with PTSD.Objective: The purpose of this study was to ...
Candice M. Monson   +15 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Prolonged Exposure Therapy For Post Traumatic Stress Disorder

open access: yes, 2012
Post-traumatic Stress Disorder (PTSD) is a psychiatric illness that usually develops after an event that threatens one’s life and body integrity and it affects quality of life and impairs social functioning significantly.
Selçuk ASLAN   +3 more
core  

Prolonged Exposure Therapy for Veterans with Post Traumatic Stress Disorder [PDF]

open access: yes, 2016
Posttraumatic stress disorder (PTSD) is the mental health condition that is triggered by the experience of a traumatic event and results in mental and physical health problems as well as interpersonal and social problems (Foa, Gillihan, and Bryant, 2013).
Livingston, Courtney Maxine
core  

Prolonged exposure to the candidate microbicide C31G differentially reduces cellular sensitivity to agent re-exposure

open access: yes, 2005
Comparative assays of in vitro cytotoxicity using nonoxynol-9 (N-9) and the candidate microbicides C31G and sodium dodecyl sulfate (SDS) demonstrated that these agents, which are, respectively, characterized as nonionic, amphoteric, and anionic ...
Catalone, Bradley J.   +9 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Effects of catecholamines on hepatic and skeletal muscle mitochondrial respiration after prolonged exposure to faecal peritonitis in pigs

open access: yes, 2011
Use of norepinephrine to increase blood pressure in septic animals has been associated with increased efficiency of hepatic mitochondrial respiration. The aim of this study was to evaluate whether the same effect could be reproduced in isolated hepatic ...
Schröeder, Ralph   +11 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Altered sensitivity to mechanical stimulation during prolonged subcutaneous administration of endothelin-1 in rats

open access: yes, 2009
Guy Hans1,2,3, Kristof Deseure2,3, Marcel Vercauteren1,2,31Multidisciplinary Pain Center; 2Department of Anesthesiology, Antwerp University Hospital, Edegem, Belgium; 3Laboratory of Anesthesiology and Pain Research, University of Antwerp, Wilrijk ...
Kristof Deseure   +5 more
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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