Results 41 to 50 of about 2,967 (149)

Novel and versatile solid-state chemiluminescence sensor based on TiO2-Ru(bpy)32+ nanoparticles for pharmaceutical drugs detection

open access: yesNanophotonics, 2018
This work describes a novel and versatile solid-state chemiluminescence sensor for analyte detection using TiO2-Ru(bpy)32+-Ce(IV). Herein, we report the synthesis, characterization, optimization and application of a new type of hybrid nanoparticles (NPs).
Al-Hetlani Entesar   +2 more
doaj   +1 more source

Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing

open access: yesFrontiers in Medicine, 2019
Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. In T. cruzi the transport of polyamines is essential because this organism is unable to synthesize these compounds de novo.
Chantal Reigada   +10 more
doaj   +1 more source

Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale

open access: yesGeriatrics &Gerontology International, Volume 26, Issue 1, January 2026.
ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi   +4 more
wiley   +1 more source

Integrated transcriptomics reveals master regulators of lung adenocarcinoma and novel repositioning of drug candidates

open access: yesCancer Medicine, 2019
Background Lung adenocarcinoma is the major cause of cancer‐related deaths in the world. Given this, the importance of research on its pathophysiology and therapy remains a key health issue.
Marco Antônio De Bastiani, Fábio Klamt
doaj   +1 more source

Exposure of chlorpromazine to 266 nm laser beam generates new species with antibacterial properties: contributions to development of a new process for drug discovery.

open access: yesPLoS ONE, 2013
IntroductionPhenothiazines when exposed to white light or to UV radiation undergo a variety of reactions that result in degradation of parental compound and formation of new species.
Mihail Lucian Pascu   +12 more
doaj   +1 more source

Pathogenic Significance of Trypanosomatids: Progress in Drug Resistance, Control Strategies, and Artificial Intelligence

open access: yesInterdisciplinary Perspectives on Infectious Diseases, Volume 2026, Issue 1, 2026.
Trypanosomatids, including the genera Trypanosoma and Leishmania, are protozoan parasites of significant medical and veterinary relevance. These organisms cause African trypanosomiasis, Chagas disease, and leishmaniasis, which are classified as neglected tropical diseases (NTDs).
Cynthia Mmalebna Amisigo   +13 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +206 more
wiley   +1 more source

Critical insights into the potential risks of antipsychotic drugs to fish, including through effects on behaviour

open access: yesBiological Reviews, Volume 100, Issue 5, Page 1994-2019, October 2025.
ABSTRACT Antipsychotic drugs (APDs) are a diverse class of neuroactive pharmaceuticals increasingly detected in surface and ground waters globally. Some APDs are classified as posing a high environmental risk, due, in part, to their tendency to bioaccumulate in wildlife, including fish.
Gabrielle Wasser‐Bennett   +4 more
wiley   +1 more source

Lnvestigations on effects of various biochemical parameters in blood and cerebrospinal fluid of some tranquilizers in dogs [PDF]

open access: yesEurasian Journal of Veterinary Sciences
This study was carried out in three groups, that each group consists of 5 dogs. In the first group xylazine, in the second group propionylprozmazine and third group promazine was used intravenously, as a doses of mg per kg body weight 3.5, 0.3 and 3 mg ...
Celal İZCİ   +3 more
doaj  

Sleep Spindle Abnormalities in Preschool Children With Autism Spectrum Disability: Insights From Nap Polysomnography

open access: yesAutism Research, Volume 18, Issue 9, Page 1764-1774, September 2025.
ABSTRACT Sigma power and sleep spindles are key elements of Non‐Rapid Eye Movement (NREM) sleep. They reflect anatomical and physiological properties of brain circuits, are linked with various behavioral outcomes in typically development (TD) children, and undergo significant modifications during development.
Sasha D’Ambrosio   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy