Results 51 to 60 of about 1,389,605 (343)

occumb: An R package for site occupancy modeling of eDNA metabarcoding data

open access: yesPopulation Ecology, EarlyView.
This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley   +1 more source

Quantitative Analysis of the KSHV Transcriptome Following Primary Infection of Blood and Lymphatic Endothelial Cells

open access: yesPathogens, 2017
The transcriptome of the Kaposi’s sarcoma-associated herpesvirus (KSHV/HHV8) after primary latent infection of human blood (BEC), lymphatic (LEC) and immortalized (TIME) endothelial cells was analyzed using RNAseq, and compared to long-term latency in ...
A. Gregory Bruce   +6 more
doaj   +1 more source

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

open access: yesFEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta   +3 more
wiley   +1 more source

Transcription of a 5’ extended mRNA isoform directs dynamic chromatin changes and interference of a downstream promoter

open access: yeseLife, 2017
Cell differentiation programs require dynamic regulation of gene expression. During meiotic prophase in Saccharomyces cerevisiae, expression of the kinetochore complex subunit Ndc80 is downregulated by a 5’ extended long undecoded NDC80 transcript ...
Minghao Chia   +6 more
doaj   +1 more source

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1998
Inactivation of the genes involved in DNA mismatch repair is associated with microsatellite instability (MSI) in colorectal cancer. We report that hypermethylation of the 5' CpG island of hMLH1 is found in the majority of sporadic primary colorectal ...
J. Herman   +15 more
semanticscholar   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Living community cookbook: transdisciplinary collaboration for constructing recipes with biocultural value

open access: yesEcology and Society
This research aims to delve into food knowledge and practices concerning the ecological management of food resources, spanning procurement, transformation, and consumption processes, through the lens of creating a cookbook as a tool for decolonizing food
Carolina Gutiérrez Sánchez   +5 more
doaj   +1 more source

Fitness effects of altering gene expression noise in Saccharomyces cerevisiae

open access: yeseLife, 2018
Gene expression noise is an evolvable property of biological systems that describes differences in expression among genetically identical cells in the same environment.
Fabien Duveau   +7 more
doaj   +1 more source

DeePromoter: Robust Promoter Predictor Using Deep Learning

open access: yesFrontiers in Genetics, 2019
The promoter region is located near the transcription start sites and regulates transcription initiation of the gene by controlling the binding of RNA polymerase.
Mhaned Oubounyt   +3 more
semanticscholar   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

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