Results 161 to 170 of about 466,642 (309)

Modular synthetic cross-kingdom promoters enable coordinated expression in Escherichia coli and Saccharomyces cerevisiae. [PDF]

Nucleic Acids Res
Son SH, Moon SY, An NY, Lee JY.
europepmc   +1 more source

Analyzing Synthetic Promoters Using Arabidopsis Protoplasts

, 2016
Stracke R, Thiedig K, Kuhlmann M, Weisshaar B. Analyzing Synthetic Promoters Using Arabidopsis Protoplasts. In: Hehl R, ed. Plant Synthetic Promoters. Methods in Molecular Biology. Vol 1482.
Stracke, Ralf ; https://orcid.org/, Kuhlmann, Melanie, Thiedig, Katharina, Weisshaar, Bernd ; https://orcid.org/, Hehl, Reinhard   +4 more
core  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

miR2Meth: An R package for dissecting DNA methylation heterogeneity at microRNA promoters. [PDF]

Quant Biol
Shan Y, Rong X, Teschendorff AE, Yang Z.
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Combinatorial cis-regulatory elements shape temporal effector expression in Ustilago maydis. [PDF]

Mol Plant Pathol
Saridis G, Werner J, Stein K, Huang L, Meyer U, Muelhoefer J, Singh NC, Doehlemann G.   +7 more
europepmc   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Promotion

American Journal of Health-System Pharmacy, 2019
openaire   +2 more sources

Machine learning analysis of the human initiator region reveals key features of different types of core promoters. [PDF]

Genes Dev
Rhyne-Carrigg TE, Vo Ngoc L, Medrano C, Gillespie KE, Kadonaga JT.   +4 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source