Results 71 to 80 of about 4,256,398 (299)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2005 The tables that comprise the body of this report summarise selected reviews of studies that evaluate the effectiveness of health promotion interventions to promote behaviour change in 4 main areas: alcohol consumption, tobacco smoking, physical ...
Health Promotion Strategy Unit, DHCS
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Evaluating oral health promotion: need for quality outcome measures [PDF]
, 2006 Oral health promotion effectiveness reviews have identified the need to improve the quality of the evaluation of interventions. A project was undertaken to identify and assess the quality of available outcome measures.
Fuller, SS +11 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Nairobi City County Food System Strategy 2022
, 2022 This is a food system strategy for implementing Sessional Paper Number I of2012 0111 the National Food and Nutrition Security Policy; it puts into effect the following directions of the policy: a.
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Adaptability assessment and promotion strategy of the Yellow River Water Allocation Scheme
Shui kexue jinzhan, 2019 The Yellow River Water Allocation Scheme ("Scheme 1987") provides an important foundation for basin-scale water resources management. The Scheme 1987 has been in place for more than 30 years,during which time both the natural environment and the ...
WANG Yu +5 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Improving effectiveness of the project activity of charitable foundations
Вестник университетаThe article discusses improvement of the effectiveness of the project activities of charitable foundations. The authors analyse various approaches to charity and charitable activities and reveal stages of preparation and implementation of sponsorship ...
E. A. Sokolova, P. V. Zozulya
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source