Results 61 to 70 of about 4,804,928 (276)
SSRN Electronic JournalResponsible prompt engineering has emerged as a critical framework for ensuring that generative artificial intelligence (AI) systems serve society's needs while minimizing potential harms. As generative AI applications become increasingly powerful and ubiquitous, the way we instruct and interact with them through prompts has profound implications for ...
openaire +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Automatic Prompt Engineering Technology for Large Language Models: a Survey [PDF]
Jisuanji kexue yu tansuoPrompt engineering (PE) based on prompt learning is crucial for improving the technical accessibility of LLMs and accelerating their adoption, diffusion, and application development.
BA Zezhi, ZHANG Hui, XIE Zhenghan, ZUO Xiaodong, HOU Jianwei
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Prompt Engineering Guide: Scriptwriting Prompt Guide [PDF]
Prompt engineering guide for scriptwriting.
McMillion, Tonya
core +1 more source
Ekphrasis and prompt engineering
Studi di EsteticaIn this work I try to show that there is a common thread between ekphrasis and prompt engineering, in spite of the temporal distance of almost thirty centuries between their respective earliest known instances, and despite the blatant disparity in ...
Mario Verdicchio
doaj
Application of Prompt Engineering Techniques to Optimize Information Retrieval in the Metaverse
Journal of MetaversePrompt engineering techniques are instructions that enable large language models (LLMs) to solve real-world problems more effectively. These techniques enhance the capabilities of LLMs to generate accurate and efficient responses.
Asım Sinan Yüksel +2 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source