Results 61 to 70 of about 2,666 (246)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Improving English Pronunciation: An Automated Instructional Approach

Information Technologies and International Development, 2003
This paper describes an experiment in which groups of children attempted to improve their English pronunciation using an English-language learning software, some English films, and a speech-to-text software engine. The experiment was designed to examine two hypotheses.
Mitra S, Tooley JN, Inamdar P, Dixon P
openaire   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Pronunciation instruction in digital EFL programs at Indonesian university: Pedagogical challenges and opportunities

English Learning Innovation
The use of digital technology has significantly transformed traditional pedagogical practice for pronunciation instruction. Numerous studies have explored the positive and negative impact of digital tools in pronunciation instruction, yet only a limited
Yuliyanto Sabat, Abd. Syakur, Lailatul Musyarofah   +2 more
doaj  

The Effect of Explicit Pronunciation Instruction on Undergraduate EFL Learners' Vowel Perception

Language and Literacy: A Canadian Educational e-journal, 2016
Since English pronunciation errors are often caused by the transfer of the Persian language sound system, the present study investigated the effect of explicit pronunciation instruction on undergraduate English as a Foreign Language (EFL) learners’ vowel
Mohammad Reza Ghorbani, Malihe Neissari, Hamid Reza Kargozari   +2 more
doaj   +1 more source

Approaches to Pronunciation Instruction in Communicative Language Teaching Classrooms

Journal of Studies in Education, 2021
One of the main factors that affects pronunciation instruction in the classroom is the educators’ teaching approach. Various elements like L1 (first language), cultural backgrounds, et cetera would influence teaching pronunciation, making English teachers deploy different pedagogical approaches for the learning process to occur.
openaire   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Teaching and Learning Pronunciation through Instructional Pronunciation Video at Sman 4 Sampolawa

Journal of Teaching of English, 2021
This research was conducted to find out whether there is a significant effect of using Instructional Pronunciation Video on students’ pronunciation ability at ten grade students of SMAN 4 Sampolawa. The design of the research was quasi-experimental design consisting of experimental and control class. The total population was 42 students which consisted
Potto, Mardiana, Jaya, Amir, Siam, Siam
openaire   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

English Pronunciation Instruction: Views and Recommendations

Journal of Language Teaching and Research, 2017
Despite decades of advocacy for greater attention, research into pronunciation instruction in English language teaching continues to be restricted. This article provides a comprehensive review of some important issues of English pronunciation instruction.
openaire   +1 more source