Results 51 to 60 of about 168,416,722 (298)

Coalition-proof supply function equilibria under capacity constraints [PDF]

open access: yes, 2005
Whereas in the absence of capacity constraints the Cournot outcome is the unique coalition-proof supply function equilibrium outcome, the presence of capacity constraints may enlarge the set of equilibrium outcomes.
Delgado, Juan
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

HealthDote: A blockchain-based model for continuous health monitoring using interplanetary file system

open access: yesHealthcare Analytics, 2023
The Healthcare industry demands increased privacy and security to protect confidential patient information and comply with regulations. Both these features can be incorporated into the existing systems using Blockchain technology.
Sireejaa Uppal   +3 more
doaj   +1 more source

Blink: An Optimal Proof of Proof-of-Work

open access: yes
Blockchain interoperability solutions allow users to hold and transfer assets among different chains, and in so doing reap the benefits of each chain. To fully reap the benefits of multi-chain financial operations, it is paramount to support interoperability and cross-chain transactions also on Layer-2 networks, in particular payment channel networks ...
Aumayr, Lukas   +4 more
openaire   +4 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Proof Planning [PDF]

open access: yes, 1995
We describe proof planning, a technique for the global control of search in automatic theorem proving. A proof plan captures the common patterns of reasoning in a family of similar proofs and is used to guide the search for new proofs in this family ...
Bundy, Alan
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

THE USE OF BLOCKCHAINS. AN R APPROACH [PDF]

open access: yesChallenges of the Knowledge Society, 2018
The cryptocurrency is a hot topic and understanding the blockchain is very important. Also, understanding what blockchain may lead to more decentralized services and applications to be used, not only in relation to financial applications.
Nicolae-Marius JULA, Nicoleta JULA
doaj  

Proof of Work as a Three-Sided Market

open access: yesFrontiers in Blockchain, 2020
Blockchain technology is the distributed ledger technology underlying Bitcoin and other cryptocurrencies. We apply Oliver Williamson's transactions cost analysis to a proof of work blockchain consensus mechanism.
Chris Berg   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy