Results 61 to 70 of about 168,416,722 (298)

Valuable Puzzles for Proofs-of-Work [PDF]

open access: yes, 2018
Proof-of-work (PoW) is used as the consensus mechanism in most cryptocurrencies. PoW-based puzzles play an important part in the operation and security of a cryptocurrency, but come at a considerable energy cost. One approach to the problem of energy wastage is to find ways to build PoW schemes from valuable computational problems.
Boyd, Colin Alexander, Carr, Christopher
openaire   +2 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Putting the Burden of Proof in Its Place: When Are Differential Allocations Legitimate? [PDF]

open access: yes, 2008
It is widely assumed that legitimate differential allocations of the burden of proof are ubiquitous: that in all cases in which opposing views are being debated, one side has the responsibility of proving their claim and if they fail, the opposing view ...
Kingsbury, Justine   +2 more
core   +1 more source

Continuous Patient Monitoring With a Patient Centric Agent: A Block Architecture

open access: yesIEEE Access, 2018
The Internet of Things (IoT) has facilitated services without human intervention for a wide range of applications, including continuous remote patient monitoring (RPM).
Md. Ashraf Uddin   +3 more
doaj   +1 more source

Implementasi Teknologi Blockchain Proof of Work Pada Penelusuran Supply Chain Produk Komputer

open access: yesJurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), 2021
In recent times, the supply chain has developed into a large ecosystem. Various products moving from party to party require cooperation between stakeholders in managing the data generated. The problem is that every company has its own transaction records
Annisya, Emy Haryatmi
doaj   +1 more source

PoSAT: Proof-of-Work Availability and Unpredictability, Without the Work

open access: yes, 2021
An important feature of Proof-of-Work (PoW) blockchains is full dynamic availability, allowing miners to go online and offline while requiring only 50% of the online miners to be honest. Existing Proof-of-stake (PoS), Proof-of-Space and related protocols are able to achieve this property only partially, either putting the additional assumption that ...
Soubhik Deb, Sreeram Kannan, David Tse
openaire   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Secure Implementation: Strategy-Proof Mechanisms Reconsidered [PDF]

open access: yes
Strategy-proofness, requiring that truth-telling is a dominant strategy, is a standard concept in social choice theory. However, the concept of strategy-proofness has serious drawbacks. First, announcing one's true preference may not be a unique dominant
Sjostrom, Tomas   +2 more
core   +2 more sources

THE IMPACT OF ENERGY CONSUMPTION IN CRYPTO ASSETS ON CRYPTO ASSET PRICES AND CARBON EMISSIONS: CASE OF BITCOIN AND ETHEREUM [PDF]

open access: yesFinancial Studies
In this paper, it is aimed to evaluate the relationship between energy consumption in crypto assets and crypto asset prices. In this direction, the price, CO2 emission and energy consumption series of Bitcoin and Ethereum between March 17, 2021, and ...
Meltem BİLİRER, Feyyaz ZEREN
doaj  

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